Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | THPO | P40225 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | BLM | P54132 | 2/20 | 0.48 |
| ▸ | GMNN | O75496 | 1/20 | 0.48 |
| ▸ | GFER | P55789 | 1/20 | 0.48 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17320175 | 0.88 | CA1 (0.52) | MAPTMAPK1HIF1AHSD17B10TP53 | |
| SCHEMBL24346426 | 0.80 | HTT (0.46) | MAPTMAPK1HIF1AHSD17B10TP53 | |
| SCHEMBL24202036 | 0.76 | TMEM97 (0.59) | MAPTMAPK1HIF1AHSD17B10TP53 | |
| SCHEMBL26324657 | 0.74 | HPGD (0.49) | MAPTTP53ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL2220683 | 0.70 | MAPT (0.53) | MAPTMAPK1ALOX15KDM4EALDH1A1 | |
| SCHEMBL2220680 | 0.70 | MAPT (0.53) | MAPTMAPK1ALOX15KDM4EALDH1A1 | |
| SCHEMBL13523477 | 0.70 | CA1 (0.46) | TP53ALDH1A1SMN1; SMN2THRBCA1 | |
| SCHEMBL13820249 | 0.69 | CA1 (0.58) | MAPTMAPK1HSD17B10ALOX15KDM4E | |
| SCHEMBL1298805 | 0.69 | THRB (0.41) | MAPTMAPK1THRBCA1CA2 | |
| SCHEMBL1298802 | 0.69 | THRB (0.41) | MAPTMAPK1THRBCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015187019-A1 | CLEAVAGE AND EXCHANGE OF MAJOR HISTOCOMPATIBILITY COMPLEX LIGANDS EMPLOYING AZOBENZENE-CONTAINING PEPTIDES | STICHTING SANQUIN BLOEDVOORZIENING (NL) | 2015-12-10 | — | — | WO | disclosed |