Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 7/20 | 0.85 |
| ▸ | AMY1A | P0DUB6 | 3/20 | 0.85 |
| ▸ | NPC1 | O15118 | 6/20 | 0.85 |
| ▸ | MEN1 | O00255 | 6/20 | 0.85 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.85 |
| ▸ | RAB9A | P51151 | 5/20 | 0.85 |
| ▸ | MAPT | P10636 | 4/20 | 0.85 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.81 |
| ▸ | GAA | P10253 | 3/20 | 0.71 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.71 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.71 |
| ▸ | TSHR | P16473 | 2/20 | 0.71 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.71 |
| ▸ | USP2 | O75604 | 1/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.71 |
| ▸ | LMNA | P02545 | 1/20 | 0.71 |
| ▸ | THRB | P10828 | 1/20 | 0.71 |
| ▸ | HPGD | P15428 | 1/20 | 0.71 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.71 |
| ▸ | HTT | P42858 | 1/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4538024 | 0.92 | ALOX5 (0.74) | ALOX5AMY1ANPC1MEN1KMT2A | |
| SCHEMBL12297429 | 0.92 | ALOX5 (0.74) | ALOX5AMY1ANPC1MEN1KMT2A | |
| SCHEMBL31126461 | 0.92 | ALOX5 (0.74) | ALOX5AMY1ANPC1MEN1KMT2A | |
| SCHEMBL12297401 | 0.92 | ALOX5 (0.74) | ALOX5AMY1ANPC1MEN1KMT2A | |
| SCHEMBL838274 | 0.92 | ALOX5 (0.74) | ALOX5AMY1ANPC1MEN1KMT2A | |
| SCHEMBL1886814 | 0.92 | RAB9A (1.00) | ALOX5AMY1ANPC1MEN1KMT2A | |
| SCHEMBL1819906 | 0.92 | RAB9A (0.78) | ALOX5AMY1ANPC1MEN1KMT2A | |
| SCHEMBL10072694 | 0.92 | ALOX5 (0.74) | ALOX5AMY1ANPC1MEN1KMT2A | |
| SCHEMBL12297873 | 0.90 | ALOX5 (0.71) | ALOX5AMY1ANPC1MEN1KMT2A | |
| SCHEMBL12297395 | 0.90 | PTGS2 (1.00) | ALOX5AMY1ANPC1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2795322-B1 | A RAPID QUANTITATIVE ASSAY TO MEASURE CFTR FUNCTION IN A PRIMARY INTESTINAL CULTURE MODEL | UMC UTRECHT HOLDING BV (NL) | 2015-12-09 | — | — | EP | disclosed |