Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | PSMB5 | P28074 | 3/20 | 0.36 |
| ▸ | METAP1 | P53582 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CTSS | P25774 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MME | P08473 | 1/20 | 0.33 |
| ▸ | ACE | P12821 | 1/20 | 0.33 |
| ▸ | CPA1 | P15085 | 1/20 | 0.33 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CTSD | P07339 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17323363 | 0.88 | METAP1 (0.35) | METAP1MEN1KMT2A | |
| SCHEMBL17323364 | 0.86 | METAP1 (0.35) | PSMB5METAP1 | |
| SCHEMBL15840394 | 0.82 | HTT (0.40) | L3MBTL1HTTCTSSCTSKMEN1 | |
| SCHEMBL22037289 | 0.78 | L3MBTL1 (0.39) | L3MBTL1HTTCTSSCTSKMEN1 | |
| SCHEMBL18558136 | 0.78 | HTT (0.53) | L3MBTL1HTTCTSSCTSKKMT2A | |
| SCHEMBL17323400 | 0.77 | PSMB5 (0.36) | L3MBTL1PSMB5METAP1CTSSCTSK | |
| SCHEMBL30493798 | 0.77 | MEN1 (0.45) | L3MBTL1HTTCTSSCTSKMEN1 | |
| SCHEMBL5177757 | 0.76 | HTT (0.42) | L3MBTL1HTTCTSSCTSKKDM4E | |
| SCHEMBL17323365 | 0.73 | CTSL (0.36) | MEN1KMT2AKDM4E | |
| SCHEMBL20342218 | 0.70 | PTPN1 (0.40) | L3MBTL1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015185467-A1 | PEPTIDES AS OXYTOCIN AGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 2015-12-10 | — | — | WO | disclosed |