Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | CTSS | P25774 | 2/20 | 0.41 |
| ▸ | CTSK | P43235 | 1/20 | 0.41 |
| ▸ | MME | P08473 | 2/20 | 0.41 |
| ▸ | ACE | P12821 | 2/20 | 0.41 |
| ▸ | CPA1 | P15085 | 2/20 | 0.41 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | ANPEP | P15144 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
| ▸ | CTSB | P07858 | 1/20 | 0.36 |
| ▸ | ENPEP | Q07075 | 2/20 | 0.36 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.34 |
| ▸ | HSPA2 | P54652 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30493798 | 0.88 | MEN1 (0.45) | HTTL3MBTL1KDM4ECTSSCTSK | |
| SCHEMBL5177757 | 0.87 | HTT (0.42) | HTTL3MBTL1KDM4ECTSSCTSK | |
| SCHEMBL15840394 | 0.84 | HTT (0.40) | HTTL3MBTL1KDM4ECTSSCTSK | |
| SCHEMBL22037289 | 0.81 | L3MBTL1 (0.39) | HTTL3MBTL1KDM4ECTSSCTSK | |
| SCHEMBL17323366 | 0.78 | L3MBTL1 (0.42) | HTTL3MBTL1KDM4ECTSSCTSK | |
| SCHEMBL20366038 | 0.78 | MME (0.46) | HTTL3MBTL1KDM4EMMEACE | |
| SCHEMBL26255783 | 0.77 | TERT (0.49) | MMEACECPA1ACE2 | |
| SCHEMBL9051957 | 0.77 | CA1 (0.45) | HTTL3MBTL1KDM4EMMEACE | |
| SCHEMBL3281647 | 0.76 | ALDH1A1 (0.63) | HTTL3MBTL1KDM4EMMEACE | |
| SCHEMBL3281651 | 0.76 | ALDH1A1 (0.63) | HTTL3MBTL1KDM4EMMEACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9579307-B2 | Amide derivatives of N-urea substituted amino acids as formyl peptide receptor like-1 (FPRL-1) receptor modulators | ALLERGAN, INC. (US) | 2017-02-28 | — | — | US | disclosed |