Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.56 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.56 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.56 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.56 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.56 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.56 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.56 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.56 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.56 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.56 |
| ▸ | BCHE | P06276 | 3/20 | 0.55 |
| ▸ | ACHE | P22303 | 3/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1732760 | 0.89 | KDM4E (0.60) | KMT2AMEN1HDAC1HDAC2RAB9A | |
| SCHEMBL7481920 | 0.88 | ALDH1A1 (0.52) | KMT2AMEN1HDAC1HDAC2RAB9A | |
| SCHEMBL1732832 | 0.87 | KDM4E (0.62) | KMT2AMEN1BCHEACHERAB9A | |
| SCHEMBL1733226 | 0.87 | KDM4E (0.51) | KMT2AHDAC1HDAC2RAB9ANPC1 | |
| SCHEMBL1732680 | 0.86 | ALDH1A1 (0.49) | KMT2AHDAC1HDAC2RAB9ANPC1 | |
| SCHEMBL1733025 | 0.83 | RAB9A (0.59) | KMT2AMEN1HDAC1HDAC2HDAC3 | |
| SCHEMBL1732263 | 0.83 | EPHX2 (0.53) | KMT2AMEN1HDAC1HDAC2RAB9A | |
| SCHEMBL1733491 | 0.83 | KDM4E (0.61) | KMT2AMEN1RAB9ANPC1ALDH1A1 | |
| SCHEMBL1732450 | 0.83 | LMNA (0.51) | KMT2AMEN1HDAC1HDAC2RAB9A | |
| SCHEMBL7483481 | 0.82 | KDM4E (0.54) | KMT2AMEN1HDAC1HDAC2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9066912-B2 | Drug-enhanced adhesion prevention | ETHICON, INC. (US) | 2015-06-30 | — | — | US | claimed |
| EP-2035008-B1 | COMPOSITIONS AND METHODS FOR PREVENTING OR REDUCING POSTOPERATIVE ILEUS AND GASTRIC STASIS IN MAMMALS | ETHICON INC (US) | 2011-11-23 | — | — | EP | claimed |
| EP-1732486-A4 | DRUG-ENHANCED ADHESION PREVENTION | ETHICON INC (US) | 2009-04-08 | — | — | EP | claimed |
| EP-2035008-A2 | COMPOSITIONS AND METHODS FOR PREVENTING OR REDUCING POSTOPERATIVE ILEUS AND GASTRIC STASIS IN MAMMALS | Ethicon, Incorporated (US) | 2009-03-18 | — | — | EP | claimed |
| WO-2007146920-A2 | COMPOSITIONS AND METHODS FOR PREVENTING OR REDUCING POSTOPERATIVE ILEUS AND GASTRIC STASIS IN MAMMALS | ETHICON, INC. (US) | 2007-12-21 | — | — | WO | claimed |
| US-20070286892-A1 | COMPOSITIONS AND METHODS FOR PREVENTING OR REDUCING POSTOPERATIVE ILEUS AND GASTRIC STASIS IN MAMMALS | ETHICON, INC. | 2007-12-13 | — | — | US | claimed |
| JP-2007528391-A | — | — | 2007-10-11 | — | — | JP | claimed |
| EP-1732486-A1 | DRUG-ENHANCED ADHESION PREVENTION | ETHICON, INC. (US) | 2006-12-20 | — | — | EP | claimed |
| WO-2005092264-A1 | DRUG-ENHANCED ADHESION PREVENTION | ETHICON, INC. (US) | 2005-10-06 | — | — | WO | claimed |
| US-20050106230-A1 | Drug-enhanced adhesion prevention | ETHICON, INC. | 2005-05-19 | — | — | US | claimed |
| US-20050106229-A1 | Drug-enhanced adhesion prevention | ETHICON, INC. | 2005-05-19 | — | — | US | claimed |
| US-9066912-B2 | Drug-enhanced adhesion prevention | ETHICON, INC. (US) | 2015-06-30 | — | — | US | disclosed |
| EP-1732486-B1 | TRANILAST COMPOSITION FOR USE IN THE PREVENTION OF POSTOPERATIVE ADHESION | ETHICON INC (US) | 2014-05-07 | — | — | EP | disclosed |
| EP-2035008-B1 | COMPOSITIONS AND METHODS FOR PREVENTING OR REDUCING POSTOPERATIVE ILEUS AND GASTRIC STASIS IN MAMMALS | ETHICON INC (US) | 2011-11-23 | — | — | EP | disclosed |
| EP-2335703-A1 | Compositions and Methods for Preventing or Reducing Postoperative Ileus and Gastric Stasis in Mammals | Ethicon, Incorporated (US) | 2011-06-22 | — | — | EP | disclosed |
| US-20070286892-A1 | COMPOSITIONS AND METHODS FOR PREVENTING OR REDUCING POSTOPERATIVE ILEUS AND GASTRIC STASIS IN MAMMALS | ETHICON, INC. | 2007-12-13 | — | — | US | disclosed |
| EP-1732486-A1 | DRUG-ENHANCED ADHESION PREVENTION | ETHICON, INC. (US) | 2006-12-20 | — | — | EP | disclosed |
| WO-2005092264-A1 | DRUG-ENHANCED ADHESION PREVENTION | ETHICON, INC. (US) | 2005-10-06 | — | — | WO | disclosed |
| US-20050106229-A1 | Drug-enhanced adhesion prevention | ETHICON, INC. | 2005-05-19 | — | — | US | disclosed |
| US-20050106230-A1 | Drug-enhanced adhesion prevention | ETHICON, INC. | 2005-05-19 | — | — | US | disclosed |