Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.55 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.54 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.51 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.48 |
| ▸ | REN | P00797 | 3/20 | 0.47 |
| ▸ | FAAH | O00519 | 1/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | CNR2 | P34972 | 1/20 | 0.47 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | ITGB2 | P05107 | 2/20 | 0.45 |
| ▸ | ICAM1 | P05362 | 2/20 | 0.45 |
| ▸ | ITGAL | P20701 | 2/20 | 0.45 |
| ▸ | HRH2 | P25021 | 1/20 | 0.44 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19051549 | 0.91 | SLC15A2 (0.56) | SLC6A5SLC15A2EPHX2TBXAS1CYP3A4 | |
| SCHEMBL19051545 | 0.89 | SLC15A2 (0.53) | SLC6A5SLC15A2EPHX2TBXAS1REN | |
| SCHEMBL19051548 | 0.88 | REN (0.57) | SLC6A5SLC15A2REN | |
| SCHEMBL19059414 | 0.87 | SLC6A5 (0.70) | SLC6A5SLC15A2EPHX2TBXAS1CYP3A4 | |
| SCHEMBL19051546 | 0.87 | SLC15A2 (0.52) | SLC6A5SLC15A2EPHX2TBXAS1REN | |
| SCHEMBL18857761 | 0.86 | SLC15A2 (0.58) | SLC6A5SLC15A2EPHX2CPB2HRH2 | |
| SCHEMBL19051564 | 0.86 | SLC15A2 (0.51) | SLC6A5SLC15A2EPHX2TBXAS1REN | |
| SCHEMBL21852767 | 0.85 | ERAP2 (0.54) | SLC6A5RENHRH2HRH4 | |
| SCHEMBL19051550 | 0.83 | SLC15A2 (0.61) | SLC6A5SLC15A2EPHX2TBXAS1CYP3A4 | |
| SCHEMBL18381256 | 0.83 | SLC6A5 (0.57) | SLC6A5SLC15A2EPHX2TBXAS1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9353154-B2 | Compositions for labeling nerves and methods of use | AVELAS BIOSCIENCES, INC. (US) | 2016-05-31 | — | — | US | disclosed |
| US-20150353604-A1 | COMPOSITIONS FOR LABELING NERVES AND METHODS OF USE | AVELAS ACQUISITION CORPORATION | 2015-12-10 | — | — | US | disclosed |