Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.54 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.54 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.54 |
| ▸ | REN | P00797 | 2/20 | 0.52 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.52 |
| ▸ | HRH2 | P25021 | 1/20 | 0.52 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.52 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.51 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20133407 | 0.94 | REN (0.61) | ERAP2ERAP1LNPEPREN | |
| SCHEMBL17325320 | 0.85 | SLC6A5 (0.55) | RENHRH2HRH4SLC6A5 | |
| SCHEMBL18862444 | 0.82 | REN (0.55) | ERAP2ERAP1LNPEPRENHRH3 | |
| SCHEMBL18857761 | 0.81 | SLC15A2 (0.58) | HRH3HRH2HRH4SLC6A5 | |
| SCHEMBL3392405 | 0.80 | SLC6A5 (0.48) | RENSLC6A5 | |
| SCHEMBL14233122 | 0.80 | MMP2 (0.55) | ERAP2ERAP1LNPEPRENHRH3 | |
| SCHEMBL13007878 | 0.80 | SLC6A5 (0.48) | RENSLC6A5 | |
| SCHEMBL18862365 | 0.80 | REN (0.67) | ERAP2ERAP1LNPEPREN | |
| SCHEMBL18857602 | 0.79 | REN (0.64) | ERAP2ERAP1LNPEPREN | |
| SCHEMBL30030926 | 0.79 | MME (0.59) | ERAP2ERAP1LNPEPREN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200108159-A1 | RADIOTHERAPEUTIC AND COMPANION IMAGING AGENTS TO TARGET MC1R | WAKE FOREST UNIVERSITY | 2020-04-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200108159-A1 | RADIOTHERAPEUTIC AND COMPANION IMAGING AGENTS TO TARGET MC1R | MC1R, MC3R, MC5R | ERAP2 2037/4885ERAP1 2020/4885LNPEP 1010/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.