SCHEMBL17327481

SCHEMBL17327481

Nc1ccc(NCc2ccncn2)c(N)c1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KCNH3 Q9ULD8 1/20 0.42
MAOA P21397 1/20 0.39
MAOB P27338 1/20 0.39
ADRA2B P18089 1/20 0.36
HSP90AA1 P07900 1/20 0.35
PDE1A P54750 2/20 0.33
PDE1B Q01064 2/20 0.33
PDE1C Q14123 2/20 0.33
EGFR P00533 4/20 0.33
P2RX7 Q99572 1/20 0.32
CHRM4 P08173 1/20 0.32
ATAD2 Q6PL18 1/20 0.32
HPGDS O60760 1/20 0.31
NAMPT P43490 1/20 0.31
RPS6KB1 P23443 1/20 0.31
AKT1 P31749 1/20 0.31
IGF1R P08069 1/20 0.31
HRH4 Q9H3N8 1/20 0.31
ADORA2A P29274 1/20 0.31
ADORA2B P29275 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27609248 0.71 KCNH3 (0.56) KCNH3MAOAMAOBHSP90AA1P2RX7
SCHEMBL13428036 0.70 ALDH1A1 (0.55) RPS6KB1AKT1
SCHEMBL10188167 0.69
SCHEMBL18157948 0.68 KCNH3 (0.47) KCNH3HSP90AA1P2RX7CHRM4HPGDS
SCHEMBL6269549 0.68 PRSS1 (0.40) ADRA2B
SCHEMBL17327480 0.68 MEN1 (0.49)
SCHEMBL20584182 0.67 MAOA (0.60) MAOAMAOBATAD2
SCHEMBL25721289 0.66 MAOA (0.51) MAOAMAOBATAD2RPS6KB1
SCHEMBL14318036 0.66 MAOA (0.51) MAOAMAOBATAD2
SCHEMBL4028848 0.66 MAPT (0.61) MAOAMAOBATAD2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9404041-B2 Liquid crystal alignment agent, liquid crystal alignment film, and liquid crystal display element CHI MEI CORPORATION (TW) 2016-08-02 US disclosed
US-20150353829-A1 LIQUID CRYSTAL ALIGNMENT AGENT, LIQUID CRYSTAL ALIGNMENT FILM, AND LIQUID CRYSTAL DISPLAY ELEMENT CHI MEI CORPORATION (TW) 2015-12-10 US disclosed