Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 1/20 | 0.95 |
| ▸ | PPARD | Q03181 | 1/20 | 0.95 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.95 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.95 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.59 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.56 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.50 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.47 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.47 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.47 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1732565 | 1.00 | LCK (0.95) | LCKPPARDZDHHC20ZDHHC2ZDHHC7 | |
| SCHEMBL1036505 | 1.00 | LCK (0.95) | LCKPPARDZDHHC20ZDHHC2ZDHHC7 | |
| SCHEMBL338250 | 0.98 | LCK (1.00) | LCKPPARDZDHHC20ZDHHC2ZDHHC7 | |
| SCHEMBL2721068 | 0.98 | LCK (1.00) | LCKPPARDZDHHC20ZDHHC2ZDHHC7 | |
| SCHEMBL337479 | 0.98 | LCK (1.00) | LCKPPARDZDHHC20ZDHHC2ZDHHC7 | |
| SCHEMBL23829555 | 0.98 | LCK (1.00) | LCKPPARDZDHHC20ZDHHC2ZDHHC7 | |
| SCHEMBL10595854 | 0.98 | LCK (1.00) | LCKPPARDZDHHC20ZDHHC2ZDHHC7 | |
| SCHEMBL375050 | 0.98 | LCK (1.00) | LCKPPARDZDHHC20ZDHHC2ZDHHC7 | |
| SCHEMBL3790420 | 0.98 | LCK (1.00) | LCKPPARDZDHHC20ZDHHC2ZDHHC7 | |
| SCHEMBL338237 | 0.98 | LCK (1.00) | LCKPPARDZDHHC20ZDHHC2ZDHHC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8540966-B2 | Contrast agents endowed with high relaxivity | BRACCO IMAGING S.P.A. (IT) | 2013-09-24 | — | — | US | disclosed |
| US-8105567-B2 | Multidentate AZA ligands able to complex metal ions and the use thereof in diagnostics and therapy | BRACCO IMAGING SPA (IT) | 2012-01-31 | — | — | US | disclosed |
| EP-1852433-B1 | CARBAZOLE DERIVATIVE, SOLVATE THEREOF, OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF | ZERIA PHARM CO LTD (JP) | 2011-11-23 | — | — | EP | disclosed |
| US-20110256067-A1 | Contrast agents endowed with high relaxivity | BRACCO IMAGING SPA (IT) | 2011-10-20 | — | — | US | disclosed |
| US-20110082280-A1 | Methods Of Coupling Multidentate AZA Ligands To Targeting Molecules | BRACCO IMAGING S.P.A. (IT) | 2011-04-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110256067-A1 | Contrast agents endowed with high relaxivity | SLC40A1, SLC67A1, SLC19A1 | LCK 4800/4885PPARD 3523/4885ZDHHC20 3733/4885 |
| US-20110082280-A1 | Methods Of Coupling Multidentate AZA Ligands To Targeting Molecules | CD99, CD209, PRMT9 | LCK 657/4885PPARD 3636/4885ZDHHC20 4733/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.