Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 1/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.62 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | F2R | P25116 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | TLR8 | Q9NR97 | 3/20 | 0.50 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.50 |
| ▸ | MPO | P05164 | 1/20 | 0.49 |
| ▸ | TNF | P01375 | 1/20 | 0.49 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.49 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.49 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27858704 | 0.84 | MMP2 (0.73) | MMP2KDM4EHTTCYP1A2CYP2D6 | |
| SCHEMBL21788572 | 0.81 | KDM4E (0.77) | MMP2KDM4EHTTNPC1TSHR | |
| SCHEMBL17824315 | 0.79 | ADORA2A (0.54) | MMP2KDM4EHTTCYP1A2CYP2D6 | |
| SCHEMBL17749550 | 0.76 | MEN1 (0.58) | KDM4EPOLBKMT2ANOD1TNF | |
| SCHEMBL14470429 | 0.75 | F2R (0.61) | HTTCYP1A2CYP2D6CXCR4F2R | |
| SCHEMBL28346903 | 0.75 | KDM4E (0.91) | MMP2KDM4EHTTPOLBLMNA | |
| SCHEMBL6199065 | 0.75 | CXCR4 (0.85) | HTTCYP1A2CYP2D6CXCR4POLB | |
| SCHEMBL20556851 | 0.74 | F2R (0.54) | HTTCYP1A2CYP2D6CXCR4POLB | |
| SCHEMBL5461909 | 0.74 | CXCR4 (0.66) | KDM4EHTTCYP1A2CYP2D6CXCR4 | |
| SCHEMBL31160335 | 0.74 | KDM4E (0.61) | MMP2KDM4EHTTNPC1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2960284-B1 | RUBBER COMPOSITION, AND PNEUMATIC TIRE USING SAME | BRIDGESTONE CORP (JP) | 2018-08-01 | — | — | EP | claimed |
| EP-2960284-A1 | RUBBER COMPOSITION, AND PNEUMATIC TIRE USING SAME | Bridgestone Corporation (JP) | 2015-12-30 | — | — | EP | claimed |
| US-20150361248-A1 | RUBBER COMPOSITION, AND PNEUMATIC TIRE USING SAME | OTSUKA CHEMICAL CO., LTD. (JP) | 2015-12-17 | — | — | US | claimed |
| US-20180319955-A1 | RUBBER COMPOSITION, AND PNEUMATIC TIRE USING SAME | BRIDGESTONE CORPORATION (JP) | 2018-11-08 | — | — | US | disclosed |
| US-10053553-B2 | Rubber composition, and pneumatic tire using same | BRIDGESTONE CORPORATION (JP) | 2018-08-21 | — | — | US | disclosed |
| EP-2960284-B1 | RUBBER COMPOSITION, AND PNEUMATIC TIRE USING SAME | BRIDGESTONE CORP (JP) | 2018-08-01 | — | — | EP | disclosed |
| US-9890267-B2 | Rubber composition for tires and pneumatic tire | BRIDGESTONE CORPORATION (JP) | 2018-02-13 | — | — | US | disclosed |
| EP-2977401-B1 | RUBBER COMPOSITION FOR TIRES AND PNEUMATIC TIRE | BRIDGESTONE CORP (JP) | 2017-06-14 | — | — | EP | disclosed |
| EP-2977401-A1 | RUBBER COMPOSITION FOR TIRES AND PNEUMATIC TIRE | Bridgestone Corporation (JP) | 2016-01-27 | — | — | EP | disclosed |
| US-20160017124-A1 | RUBBER COMPOSITION FOR TIRES AND PNEUMATIC TIRE | BRIDGESTONE CORPORATION (JP) | 2016-01-21 | — | — | US | disclosed |
| EP-2960284-A1 | RUBBER COMPOSITION, AND PNEUMATIC TIRE USING SAME | Bridgestone Corporation (JP) | 2015-12-30 | — | — | EP | disclosed |
| US-20150361248-A1 | RUBBER COMPOSITION, AND PNEUMATIC TIRE USING SAME | OTSUKA CHEMICAL CO., LTD. (JP) | 2015-12-17 | — | — | US | disclosed |
| US-20150361248-A1 | RUBBER COMPOSITION, AND PNEUMATIC TIRE USING SAME | OTSUKA CHEMICAL CO., LTD. (JP) | 2015-12-17 | — | — | US | disclosed |