Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 1/20 | 0.73 |
| ▸ | LMNA | P02545 | 4/20 | 0.67 |
| ▸ | TSHR | P16473 | 1/20 | 0.67 |
| ▸ | HTT | P42858 | 1/20 | 0.67 |
| ▸ | GSK3B | P49841 | 7/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.64 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12497263 | 0.87 | LMNA (0.69) | LMNATSHRHTTGSK3BMEN1 | |
| SCHEMBL14575429 | 0.86 | TSHR (0.62) | MMP2LMNATSHRHTTGSK3B | |
| SCHEMBL17329330 | 0.84 | MMP2 (0.67) | MMP2LMNATSHRHTTKDM4E | |
| SCHEMBL5252741 | 0.83 | LMNA (0.60) | LMNATSHRHTTGSK3B | |
| SCHEMBL21788572 | 0.83 | KDM4E (0.77) | MMP2TSHRHTTKDM4E | |
| SCHEMBL3587930 | 0.81 | KDM4E (0.69) | LMNATSHRHTTGSK3BKDM4E | |
| SCHEMBL11400323 | 0.81 | KDM4E (0.62) | LMNATSHRHTTGSK3BKDM4E | |
| SCHEMBL20715449 | 0.81 | KMT2A (0.76) | LMNATSHRHTTGSK3BKDM4E | |
| SCHEMBL3430135 | 0.81 | LMNA (1.00) | LMNATSHRHTTGSK3BMEN1 | |
| SCHEMBL12495433 | 0.81 | ALDH1A1 (0.72) | LMNATSHRHTTGSK3BKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102512413-A | 2-alkyl-benzimidazole-1-acetyl hydrazone and its application | UNIV ZHEJIANG SCIENCE & TECH | 2012-06-27 | — | — | CN | disclosed |