Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2R | P25116 | 1/20 | 0.61 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.53 |
| ▸ | CXCR3 | P49682 | 3/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.51 |
| ▸ | CTSD | P07339 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | ALPL | P05186 | 2/20 | 0.50 |
| ▸ | ALPG | P10696 | 2/20 | 0.50 |
| ▸ | ALPP | P05187 | 1/20 | 0.50 |
| ▸ | PLAA | Q9Y263 | 1/20 | 0.50 |
| ▸ | GUSB | P08236 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL484344 | 0.82 | F2R (0.57) | F2RNOD1CYP2C9CYP2C19CYP1A2 | |
| SCHEMBL20556851 | 0.77 | F2R (0.54) | F2RNOD1CYP1A2CYP2D6HTT | |
| SCHEMBL17329330 | 0.75 | MMP2 (0.67) | F2RNOD1CYP1A2CYP2D6KMT2A | |
| SCHEMBL5452572 | 0.73 | F2R (0.53) | F2RCYP1A2CYP2D6HTTCXCR4 | |
| SCHEMBL6199065 | 0.71 | CXCR4 (0.85) | NOD1CYP1A2CYP2D6KMT2AHTT | |
| SCHEMBL5461909 | 0.71 | CXCR4 (0.66) | NOD1CYP1A2CYP2D6MEN1KMT2A | |
| SCHEMBL6694492 | 0.70 | HTT (0.70) | NOD1CYP1A2CYP2D6KMT2AHTT | |
| SCHEMBL6325602 | 0.69 | SMN1; SMN2 (0.70) | CYP2C9CYP2C19CYP1A2CYP2D6MEN1 | |
| SCHEMBL1802857 | 0.69 | CXCR3 (0.57) | NOD1CYP2C9CYP2C19CYP1A2CYP2D6 | |
| SCHEMBL6196399 | 0.69 | CXCR4 (1.00) | NOD1CYP1A2CYP2D6KMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007084728-A2 | 2-IMINO-BENZIMIDAZOLES | ABBOTT LABORATORIES (US) | 2007-07-26 | — | — | WO | disclosed |