SCHEMBL1733236

SCHEMBL1733236

CC(C)(C)OC(=O)N1CCC(F)C1

nearest known ligand 0.57

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
HPGD P15428 1/20 0.53
RECQL P46063 1/20 0.50
EPHX1 P07099 1/20 0.50
USP2 O75604 1/20 0.49
SMN1; SMN2 Q16637 1/20 0.49
MAPT P10636 2/20 0.48
MEN1 O00255 1/20 0.48
ALDH1A1 P00352 1/20 0.48
KMT2A Q03164 1/20 0.48
GPR119 Q8TDV5 3/20 0.47
NR1H2 P55055 1/20 0.46
KDM4E B2RXH2 1/20 0.46
THRB P10828 1/20 0.46
PTPN2 P17706 1/20 0.46
PTPN1 P18031 1/20 0.46
PTPN6 P29350 1/20 0.46
USP30 Q70CQ3 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3792583 1.00 HPGD (0.53) HPGDRECQLEPHX1USP2SMN1; SMN2
SCHEMBL1733238 1.00 HPGD (0.53) HPGDRECQLEPHX1USP2SMN1; SMN2
Hydrochloric Acid SCHEMBL30496259 0.98 HPGD (0.51) HPGDRECQLEPHX1USP2SMN1; SMN2
SCHEMBL12524261 0.91 MEN1 (0.55) HPGDRECQLEPHX1USP2SMN1; SMN2
SCHEMBL2226544 0.91 MEN1 (0.55) HPGDRECQLEPHX1USP2SMN1; SMN2
SCHEMBL4934881 0.91 MEN1 (0.55) HPGDRECQLEPHX1USP2SMN1; SMN2
SCHEMBL25079350 0.90 HPGD (0.55) HPGDRECQLEPHX1USP2SMN1; SMN2
SCHEMBL1965735 0.89 USP2 (0.61) HPGDRECQLEPHX1USP2SMN1; SMN2
SCHEMBL16893310 0.87 CHRM2 (0.46) HPGDRECQLEPHX1USP2SMN1; SMN2
SCHEMBL12384323 0.86 NR1H2 (0.54) HPGDRECQLEPHX1USP2SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 145 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114805107-A N-alpha position arylation method of nitrogen-containing heterocycle realized by photocatalysis 哈尔滨工业大学(深圳) 2022-07-29 CN claimed
EP-4746965-A1 BENZIMIDAZOLES AS SIK-ACTIVITY MODULATORS F. Hoffmann-La Roche AG (CH) 2026-05-27 EP disclosed
US-12288848-B2 Ionic liquid electrolyte for lithium-ion batteries UCHICAGO ARGONNE, LLC (US) 2025-04-29 US disclosed
CN-119630676-A Pyrido [4,3-D ] pyrimidine derivatives as KRAS inhibitors 百时美施贵宝公司 2025-03-14 CN disclosed
CN-119569735-A Heteroaryl compounds, preparation method thereof and application thereof in medicines 江苏恒瑞医药股份有限公司 2025-03-07 CN disclosed
EP-4501932-A2 KRAS G12C INHIBITORS Mirati Therapeutics, Inc. (US) 2025-02-05 EP disclosed
WO-2025017041-A1 BENZIMIDAZOLES AS SIK-ACTIVITY MODULATORS F. HOFFMANN-LA ROCHE AG (CH) 2025-01-23 WO disclosed
EP-3880208-B1 KRAS G12C INHIBITORS MIRATI THERAPEUTICS INC (US) 2024-11-20 EP disclosed
CN-118974036-A Inhibitors of RAF kinase 皮埃尔法布雷医药公司 2024-11-15 CN disclosed
CN-112673000-B 1H-indazole carboxamides as receptor interacting protein kinase 1 inhibitors (RIPK 1) 百时美施贵宝公司 2024-10-18 CN disclosed
WO-2007008895-A1 KINASE INHIBITORS ALLERGAN, INC. (US) 2007-01-18 WO disclosed
US-7148242-B2 N-formyl hydroxylamine compounds, compositions and methods of use NOVARTIS AG (CH) 2006-12-12 US disclosed
WO-2006127576-A2 N - FORMYL HYDROXYLAMINE COMPOUNDS AS PDF INHIBITORS NOVARTIS AG (CH) 2006-11-30 WO disclosed
EP-1401828-B1 N-FORMYL HYDROXYLAMINE COMPOUNDS AS INHIBITORS OF PDF VICURON PHARM INC (US) 2006-04-12 EP disclosed
US-20050043299-A1 Inhibitors of dipeptidyl peptidase iv FERRING B. V. 2005-02-24 US disclosed
EP-1446116-A1 INHIBITORS OF DIPEPTIDYL PEPTIDASE IV FERRING B.V. (NL) 2004-08-18 EP disclosed
EP-1401828-A1 N-FORMYL HYDROXYLAMINE COMPOUNDS AS INHIBITORS OF PDF Vicuron Pharmaceuticals, Inc. (US) 2004-03-31 EP disclosed
WO-2003035057-A1 INHIBITORS OF DIPEPTIDYL PEPTIDASE IV FERRING B.V. (NL) 2003-05-01 WO disclosed
US-20030045479-A1 Novel N-formyl hydroxylamine compounds, compositions and methods of use VICURON HOLDINGS LLC 2003-03-06 US disclosed
WO-2002102790-A1 N-FORMYL HYDROXYLAMINE COMPOUNDS AS INHIBITORS OF PDF VICURON PHARMACEUTICALS INC. (US) 2002-12-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12288848-B2 Ionic liquid electrolyte for lithium-ion batteries NES, CCNI, PHOSPHO1 HPGD 4160/4885RECQL 1127/4885EPHX1 4392/4885
US-20030045479-A1 Novel N-formyl hydroxylamine compounds, compositions and methods of use PDF, HNMT, AADAC HPGD 178/4885RECQL 1455/4885EPHX1 1640/4885
US-20050043299-A1 Inhibitors of dipeptidyl peptidase iv DPP4, DPP9, DPP3 HPGD 1369/4885RECQL 2601/4885EPHX1 1134/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.