SCHEMBL1733342

SCHEMBL1733342

C=Cc1cccc(C(=O)O)c1C(C)(C)C

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 2/20 0.42
ALDH1A1 P00352 4/20 0.39
HSD17B10 Q99714 2/20 0.38
KDM4E B2RXH2 2/20 0.38
HPGD P15428 2/20 0.38
LMNA P02545 1/20 0.37
NOTUM Q6P988 1/20 0.36
POLB P06746 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
TSHR P16473 1/20 0.35
NR4A1 P22736 1/20 0.35
NR4A2 P43354 1/20 0.35
NR4A3 Q92570 1/20 0.35
CA1 P00915 2/20 0.35
CA2 P00918 2/20 0.35
MMP2 P08253 2/20 0.35
MMP1 P03956 1/20 0.35
MMP9 P14780 1/20 0.35
MMP8 P22894 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15512831 0.90 ALOX15 (0.36) ALOX15ALDH1A1HSD17B10KDM4EHPGD
SCHEMBL6552615 0.85 PARP1 (0.39) ALDH1A1HSD17B10KDM4EHPGDLMNA
SCHEMBL161622 0.81 ALOX15 (0.53) ALOX15ALDH1A1HSD17B10KDM4EHPGD
SCHEMBL31302643 0.81 LMNA (0.42) ALDH1A1HSD17B10KDM4EHPGDLMNA
SCHEMBL28064460 0.79 ALOX15 (0.52) ALOX15ALDH1A1HSD17B10KDM4EHPGD
SCHEMBL28409231 0.79 ALDH1A1 (0.41) ALDH1A1TDP1TSHRCA2
SCHEMBL5082542 0.77 TSHR (0.47) ALOX15ALDH1A1HSD17B10KDM4EHPGD
SCHEMBL7616228 0.76 HSD17B10 (0.41) ALOX15ALDH1A1HSD17B10KDM4EHPGD
SCHEMBL30259301 0.75 ALDH1A1 (0.56) ALOX15ALDH1A1HSD17B10KDM4EHPGD
SCHEMBL31100 0.75 ALDH1A1 (0.56) ALOX15ALDH1A1HSD17B10KDM4EHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2651372-B2 AEROSOL DEVICE HAVING TWO COMPARTMENTS INCLUDING AN ALCOHOLIC OR HYDROALCOHOLIC HAIRSTYLING COMPOSITION, AND HAIRSTYLING METHOD OREAL (FR) 2023-10-25 EP claimed
EP-3997138-A1 ACRYLIC POLYMER AND ADHESIVE COMPOSITIONS Henkel IP & Holding GmbH (DE) 2022-05-18 EP claimed
EP-1902077-B2 NEUTRALISED CATIONIC POLYMER, COMPOSITION CONTAINING SAID POLYMER AND A COSMETIC TREATMENT METHOD OREAL (FR) 2018-07-18 EP claimed
EP-1902077-B1 NEUTRALISED CATIONIC POLYMER, COMPOSITION CONTAINING SAID POLYMER AND A COSMETIC TREATMENT METHOD OREAL (FR) 2011-11-16 EP claimed
WO-2011133072-A1 ARRANGEMENT FOR OPERATING A HYDRAULIC DEVICE PARKER HANNIFIN AB (SE) 2011-10-27 WO claimed
EP-1043344-B1 Cosmetic composition containing star shaped polymers and their use OREAL (FR) 2003-09-03 EP claimed
EP-1043347-B1 Cosmetic composition containing star shaped polymers and their use OREAL (FR) 2003-09-03 EP claimed
EP-1043343-B1 Cosmetic composition containing star shaped polymers and their use OREAL (FR) 2003-09-03 EP claimed
EP-1043345-B1 Cosmetic composition containing star shaped polymers and their use OREAL (FR) 2003-09-03 EP claimed
EP-0897298-B1 COSMETIC AEROSOL FIXATIVE COMPOSITION PROVIDING SHINE, AND METHODS OREAL (FR) 2003-03-26 EP claimed
EP-1043346-B1 Cosmetic compositions containing star shaped polymers and their use in particular for hair OREAL (FR) 2003-03-05 EP claimed
EP-0815848-B1 Use in cosmetics of copolymers with a flexible backbone, grafted with hydrophobic and rigid macromonomers; compositions using same OREAL (FR) 2000-01-26 EP claimed
EP-0764436-B1 Aqueous cosmetic or dermatological composition comprising a filmogenic oligomer and rigid, non-filmforming nanoparticles; uses OREAL (FR) 1999-02-24 EP claimed
EP-0774248-B1 Keratinous fiber treating composition containing at least a binding polymer and at least a ceramide-type compound and methods OREAL (FR) 1999-02-10 EP claimed
EP-2641929-B1 NOVEL ORGANOPOLYSILOXANE, COSMETIC CONTAINING THEREOF, AND METHOD FOR PREPARING ORGANOPOLYSILOXANE SHINETSU CHEMICAL CO (JP) 2017-11-29 EP disclosed
US-9107855-B2 Organopolysiloxane, cosmetic containing thereof, and method for preparing organopolysiloxane SHIN-ETSU CHEMICAL CO., LTD. (JP) 2015-08-18 US disclosed
EP-1889890-B2 Method for applying a polyvinyl ester dispersion adhesive using a jet and use of polyvinyl ester dispersion adhesives CELANESE EMULSIONS GMBH (DE) 2014-06-18 EP disclosed
EP-0969063-B1 Adhesive compositions for use in package encapsulant compositions for electronic devices NAT STARCH CHEM INVEST (US) 2007-04-11 EP disclosed
EP-0969063-A2 Package encapsulant compositions for use in electronic devices National Starch and Chemical Investment Holding Corporation (US) 2000-01-05 EP disclosed
EP-0969058-A2 Method of making encapsulated electronic component with reworkable package encapsulants National Starch and Chemical Investment Holding Corporation (US) 2000-01-05 EP disclosed