⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15822081 | 0.84 | SNCA (0.32) | — | |
| SCHEMBL17336260 | 0.82 | — | — | |
| SCHEMBL17336263 | 0.82 | EGFR (0.34) | — | |
| SCHEMBL27672757 | 0.81 | TSHR (0.36) | — | |
| SCHEMBL28879804 | 0.79 | PTPRC (0.36) | — | |
| SCHEMBL23647876 | 0.75 | CA2 (0.33) | — | |
| SCHEMBL29790996 | 0.75 | CA2 (0.33) | — | |
| SCHEMBL28409734 | 0.75 | SNCA (0.33) | — | |
| SCHEMBL2936648 | 0.75 | TRPA1 (0.40) | — | |
| SCHEMBL15516408 | 0.74 | L3MBTL1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3154984-A1 | PROCESSES FOR PREPARING ANTIVIRAL COMPOUNDS | Gilead Pharmasset LLC (US) | 2017-04-19 | — | — | EP | disclosed |
| WO-2015191437-A1 | PROCESSES FOR PREPARING ANTIVIRAL COMPOUNDS | GILEAD PHARMASSET LLC (US) | 2015-12-17 | — | — | WO | disclosed |