Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 4/20 | 0.49 |
| ▸ | CA12 | O43570 | 4/20 | 0.45 |
| ▸ | CA1 | P00915 | 4/20 | 0.45 |
| ▸ | CA9 | Q16790 | 4/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | ESR1 | P03372 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TYR | P14679 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
| ▸ | ESRRG | P62508 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5379895 | 0.94 | PREP (0.53) | PREPCA12CA1CA9ESR2 | |
| SCHEMBL9843274 | 0.89 | PREP (0.42) | PREPCA12CA1CA9ESR2 | |
| SCHEMBL9841988 | 0.89 | PREP (0.42) | PREPCA12CA1CA9ESR2 | |
| SCHEMBL6763899 | 0.89 | PREP (0.53) | PREPCA12CA1CA9KDM4E | |
| 4-Hydroxybenzaldehyde SCHEMBL17494799 | 0.86 | ALDH5A1 (0.52) | PREPCA12CA1CA9MEN1 | |
| SCHEMBL2523819 | 0.83 | CA12 (0.56) | PREPCA12CA1CA9ESR2 | |
| SCHEMBL23491348 | 0.82 | PREP (0.57) | PREPCA12CA1CA9ESR2 | |
| SCHEMBL20358470 | 0.82 | PREP (0.49) | PREPCA12CA1CA9ESR2 | |
| SCHEMBL1594100 | 0.80 | CA1 (0.42) | PREPCA12CA1CA9 | |
| SCHEMBL614621 | 0.80 | PREP (0.47) | PREPCA12CA1CA9MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 143 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7772334-B2 | Crosslinker of reactive functional groups and nonionic metal coordinating structure-containing alkyl or aromatic compound | BASF COATINGS GMBH (DE) | 2010-08-10 | — | — | US | claimed |
| US-7759436-B2 | Film-former of resin with nonionic metal coordinating structure and crosslinker-reactive group | BASF COATINGS GMBH (DE) | 2010-07-20 | — | — | US | claimed |
| US-20260070884-A1 | Inhibitors of Dihydroceramide Desaturase for Treating Disease | CENTAURUS THERAPEUTICS (US) | 2026-03-12 | — | — | US | disclosed |
| US-20250216782-A1 | MASKING PROCESS USING SWITCHABLE POLYMER | TOKYO ELECTRON LTD (JP) | 2025-07-03 | — | — | US | disclosed |
| US-20250120948-A1 | Small Molecules G(alpha)I2 Inhibitors and Combination With Anticancer Drugs and Use Thereof | CLARK ATLANTA UNIVERSITY | 2025-04-17 | — | — | US | disclosed |
| CN-115710338-B | Benzoxazine resin for flexible glue-free copper-clad plate, benzoxazine monomer, and preparation method and application thereof | 成都科宜高分子科技有限公司 | 2025-03-18 | — | — | CN | disclosed |
| US-12247019-B2 | Inhibitors of dihydroceramide desaturase for treating disease | CENTAURUS THERAPEUTICS (US) | 2025-03-11 | — | — | US | disclosed |
| US-20230357187-A1 | Inhibitors of Dihydroceramide Desaturase For Treating Disease | CENTAURUS THERAPEUTICS | 2023-11-09 | — | — | US | disclosed |
| CN-111787916-B | Dihydroceramide desaturase inhibitors for treating diseases | 森陶鲁斯治疗公司 | 2023-09-05 | — | — | CN | disclosed |
| CN-111620764-B | Selective ether bond cleavage method of aryl alkyl ether | 荆楚理工学院 | 2023-05-05 | — | — | CN | disclosed |
| CN-116043242-A | Electrochemical preparation method of polysubstituted phenol derivatives | 暨南大学 | 2023-05-02 | — | — | CN | disclosed |
| US-5886019-A | REPLACEMENT OF HYDROXYMETHYL OR-ETHYL GROUP ON TRICYCLIC AROMATIC HETEROCYCLIC COMPOUNDS HAVING INDOLE, INDENE, BENZOFURAN OR BENZOTHIOPHENE SKELETON; ANTIINFLAMMATORY, ANTIVIRAL | PROCYON PHARMACEUTICALS, INC. (US) | 1999-03-23 | — | — | US | disclosed |
| US-5750568-A | DITERPENE PHORBOIDS | PROCYON PHARMACEUTICALS, INC. (US) | 1998-05-12 | — | — | US | disclosed |
| WO-1998017644-A1 | CROSS-LINKERS FOR CROSS-LINKABLE OPTICAL POLYCARBONATES | AKZO NOBEL N.V. (NL) | 1998-04-30 | — | — | WO | disclosed |
| US-5716968-A | ANTIINFLAMMATORY AGENTS; VIRICIDE | PROCYON PHARMACEUTICALS, INC. (US) | 1998-02-10 | — | — | US | disclosed |
| US-5491072-A | N-alkylacridan carboxyl derivatives useful for chemiluminescent detection | LUMIGEN, INC. (US) | 1996-02-13 | — | — | US | disclosed |
| WO-1994026927-A1 | NOVEL N-ALKYLACRIDAN CARBOXYL DERIVATIVES USEFUL FOR CHEMILUMINESCENT DETECTION | LUMIGEN, INC. (US) | 1994-11-24 | — | — | WO | disclosed |
| EP-0625156-A1 | [3H,7H]THIAZOLE[3,4-a]PYRIDINES HAVING ANTIASTHMATIC AND ANTIINFLAMNATORY ACTIVITIES ON THE RESPIRATORY TRACT | BOEHRINGER MANNHEIM ITALIA S.P.A. (IT) | 1994-11-23 | — | — | EP | disclosed |
| EP-0625510-A2 | Novel N-alkylacridan carboxyl derivatives useful for chemiluminescent detection | LUMIGEN, INC. (US) | 1994-11-23 | — | — | EP | disclosed |
| WO-1993011133-A1 | [3H,7H]THIAZOLE[3,4-a]PYRIDINES HAVING ANTIASTHMATIC AND ANTIINFLAMMATORY ACTIVITIES ON THE RESPIRATORY TRACT | BOEHRINGER MANNHEIM ITALIA S.P.A. (IT) | 1993-06-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260070884-A1 | Inhibitors of Dihydroceramide Desaturase for Treating Disease | CERS2, DEGS1, CERT1 | PREP 1491/4885CA12 3456/4885CA1 3703/4885 |
| US-12247019-B2 | Inhibitors of dihydroceramide desaturase for treating disease | CERS2, SMPD1, ASAH1 | PREP 341/4885CA12 3943/4885CA1 2374/4885 |
| US-20230357187-A1 | Inhibitors of Dihydroceramide Desaturase For Treating Disease | CERS2, SMPD1, ASAH1 | PREP 341/4885CA12 3943/4885CA1 2374/4885 |
| US-20250120948-A1 | Small Molecules G(alpha)I2 Inhibitors and Combination With Anticancer Drugs and Use Thereof | GDI2, GNAI2, GNAI3 | PREP 3720/4885CA12 4143/4885CA1 2944/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.