Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 16/20 | 0.52 |
| ▸ | PIK3R2 | O00459 | 7/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17338237 | 0.89 | PIK3CD (0.50) | PIK3CDPIK3R2SIGMAR1 | |
| SCHEMBL17338243 | 0.87 | PIK3CD (0.52) | PIK3CDPIK3R2FAAHSIGMAR1 | |
| SCHEMBL17338181 | 0.86 | PIK3CD (0.53) | PIK3CDPIK3R2SIGMAR1 | |
| SCHEMBL17338200 | 0.80 | PIK3CD (0.54) | PIK3CDPIK3R2 | |
| SCHEMBL17338353 | 0.80 | PIK3CD (0.71) | PIK3CDPIK3R2 | |
| SCHEMBL17330688 | 0.80 | PIK3CD (0.65) | PIK3CDPIK3R2 | |
| SCHEMBL17330687 | 0.80 | PIK3CD (0.65) | PIK3CDPIK3R2 | |
| SCHEMBL17338152 | 0.77 | PIK3CD (0.50) | PIK3CDPIK3R2FAAHALDH1A1 | |
| SCHEMBL17338314 | 0.76 | PIK3CD (0.53) | PIK3CDPIK3R2 | |
| SCHEMBL17338222 | 0.76 | PIK3CD (0.47) | PIK3CDPIK3R2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3154958-A1 | PHOSPHATIDYLINOSITOL 3-KINASE INHIBITORS | Gilead Sciences, Inc. (US) | 2017-04-19 | — | — | EP | disclosed |
| WO-2015191752-A1 | PHOSPHATIDYLINOSITOL 3-KINASE INHIBITORS | GILEAD SCIENCES, INC. (US) | 2015-12-17 | — | — | WO | disclosed |