SCHEMBL17338593

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL11895061	0.87	KMT2A (0.50)	NPC1RAB9ANOD2TP53RXFP1
	SCHEMBL17338580	0.86	MAPT (0.57)	TP53MAPTSMN1; SMN2KMT2AMEN1
	SCHEMBL2930311	0.85	NPC1 (0.56)	NPC1RAB9ANOD2TP53RXFP1
	SCHEMBL15956289	0.83	LMNA (0.70)	TP53ALDH1A1LMNAP2RX3
	SCHEMBL17338644	0.83	LMNA (0.69)	NPC1RAB9ANOD2TP53RXFP1
	SCHEMBL7056985	0.83	LMNA (0.69)	NPC1RAB9AMAPTSMN1; SMN2KMT2A
	SCHEMBL1549166	0.81	MAPT (0.76)	NPC1RAB9ANOD2TP53RXFP1
	SCHEMBL17338605	0.81	P2RX3 (0.57)	TP53TDP1LMNAP2RX3
	SCHEMBL23914948	0.80	KMT2A (0.60)	TP53KMT2ATDP1ALDH1A1CYP1A2
	SCHEMBL11895496	0.80	P2RX3 (0.62)	TP53LMNAP2RX3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.