Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.43 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.43 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.43 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.42 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 5/20 | 0.41 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | RXRA | P19793 | 1/20 | 0.40 |
| ▸ | RXRB | P28702 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16571317 | 0.82 | ALDH1A1 (0.38) | MAPT | |
| SCHEMBL4306909 | 0.79 | MAOB (0.52) | MEN1KMT2ANR4A2SLC16A3NR4A1 | |
| SCHEMBL8937667 | 0.76 | MEN1 (0.61) | MEN1KMT2ANR4A2NR4A1NR4A3 | |
| SCHEMBL17338654 | 0.74 | CASP3 (0.54) | MAOBACHECASP3SENP8SENP7 | |
| SCHEMBL1324010 | 0.73 | MAOB (0.56) | MEN1KMT2AMAPTMAOBACHE | |
| SCHEMBL6830612 | 0.73 | KCNA5 (0.48) | KMT2AMAPT | |
| SCHEMBL1842660 | 0.71 | MEN1 (0.55) | MEN1KMT2ANR4A2NR4A1NR4A3 | |
| SCHEMBL10657327 | 0.71 | MEN1 (0.55) | MEN1KMT2ANR4A2SLC16A3NR4A1 | |
| SCHEMBL26158656 | 0.71 | MEN1 (0.55) | MEN1KMT2ANR4A2SLC16A3NR4A1 | |
| SCHEMBL2955611 | 0.71 | LTB4R (0.64) | MEN1KMT2ANR4A2SLC16A3NR4A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015189117-A1 | HETEROBICYCLICALLY SUBSTITUTED 4-OXOBUTANE ACID DERIVATIVES AND USE THEREOF | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2015-12-17 | — | — | WO | disclosed |