Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.46 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.43 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18163838 | 0.88 | CD274 (0.53) | CD274SOS1CYP2A6CYP2C9CYP2C19 | |
| SCHEMBL183551 | 0.80 | — | — | |
| SCHEMBL901053 | 0.78 | ALDH1A1 (0.50) | CYP2A6CYP2C9CYP2C19ALDH1A1TDP1 | |
| SCHEMBL4153694 | 0.77 | CD274 (0.46) | CD274SOS1CYP2A6CYP2C9CYP2C19 | |
| SCHEMBL29111193 | 0.77 | ALDH1A1 (0.54) | CYP2A6CYP2C9CYP2C19ALDH1A1TDP1 | |
| SCHEMBL30688993 | 0.77 | ALDH1A1 (0.54) | CYP2A6CYP2C9CYP2C19ALDH1A1TDP1 | |
| SCHEMBL11368412 | 0.77 | HRH1 (0.54) | CYP2A6CYP2C9CYP2C19CYP2D6ALDH1A1 | |
| SCHEMBL20773975 | 0.77 | ALDH1A1 (0.38) | CYP2A6CYP2C9CYP2C19CYP2D6ALDH1A1 | |
| Methoxymethane SCHEMBL28429768 | 0.75 | ALDH1A1 (0.48) | CYP2A6CYP2C9CYP2C19ALDH1A1TDP1 | |
| SCHEMBL11359616 | 0.75 | CHRM2 (0.44) | CD274CYP2C9CYP2C19ALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2651910-B1 | PREPARATION OF AMINOMETHYL FURANS AND ALKOXYMETHYL FURAN DERIVATIVES FROM CARBOHYDRATES | ARCHER-DANIELS-MIDLAND COMPANY (US) | 2016-12-07 | — | — | EP | claimed |
| CN-103443090-B | Preparation of aminomethyl furan and alkoxymethyl furan derivatives from carbohydrates | 阿彻丹尼尔斯米德兰德公司 | 2016-08-24 | — | — | CN | claimed |
| US-8669383-B2 | Preparation of aminomethyl furans and alkoxymethyl furan derivatives from carbohydrates | ARCHER DANIELS MIDLAND COMPANY (US) | 2014-03-11 | — | — | US | claimed |
| CN-103443090-A | Preparation of aminomethyl furan and alkoxymethyl furan derivatives from carbohydrates | ARCHER DANIELS MIDLAND CO | 2013-12-11 | — | — | CN | claimed |
| US-20130303791-A1 | PREPARATION OF AMINOMETHYL FURANS AND ALKOXYMETHYL FURAN DERIVATIVES FROM CARBOHYDRATES | ARCHER DANIELS MIDLAND COMPANY (US) | 2013-11-14 | — | — | US | claimed |
| EP-2651910-A1 | PREPARATION OF AMINOMETHYL FURANS AND ALKOXYMETHYL FURAN DERIVATIVES FROM CARBOHYDRATES | Archer-Daniels-Midland Company (US) | 2013-10-23 | — | — | EP | claimed |
| WO-2012082665-A1 | PREPARATION OF AMINOMETHYL FURANS AND ALKOXYMETHYL FURAN DERIVATIVES FROM CARBOHYDRATES | ARCHER DANIELS MIDLAND COMPANY (US) | 2012-06-21 | — | — | WO | claimed |
| EP-4205741-A1 | USE OF COMPOUND AS CYP2E1 INHIBITOR | Shanghai Ling Xi Biotechnology Development Co., Ltd. (CN) | 2023-07-05 | — | — | EP | disclosed |
| US-10392715-B2 | Electrochemical reductive amination of furfural-based molecules | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2019-08-27 | — | — | US | disclosed |
| US-10392715-B2 | Electrochemical reductive amination of furfural-based molecules | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2019-08-27 | — | — | US | disclosed |
| US-20180057949-A1 | ELECTROCHEMICAL REDUCTIVE AMINATION OF FURFURAL-BASED MOLECULES | UNITED STATES DEPARTMENT OF ENERGY | 2018-03-01 | — | — | US | disclosed |
| US-20180057949-A1 | ELECTROCHEMICAL REDUCTIVE AMINATION OF FURFURAL-BASED MOLECULES | UNITED STATES DEPARTMENT OF ENERGY | 2018-03-01 | — | — | US | disclosed |
| US-20180057949-A1 | ELECTROCHEMICAL REDUCTIVE AMINATION OF FURFURAL-BASED MOLECULES | UNITED STATES DEPARTMENT OF ENERGY | 2018-03-01 | — | — | US | disclosed |
| WO-2003059893-A1 | N-PYRAZINYL-PHENYLSULPHONAMIDES AND THEIR USE IN THE TREATMENT OF CHEMOKINE MEDIATED DISEASES | ASTRAZENECA AB (SE) | 2003-07-24 | — | — | WO | disclosed |
| WO-2003018589-A1 | NOVEL 4-AMINOFUROPYRIMIDINES AND THE USE THEREOF | BAYER HEALTHCARE AG (DE) | 2003-03-06 | — | — | WO | disclosed |
| US-4871765-A | GASTROINTESTINAL DISORDERS | TOYAMA CHEMICAL CO., LTD. (JP) | 1989-10-03 | — | — | US | disclosed |
| US-4279819-A | GASTROINTESTINAL DISORDERS | ALLEN & HANBURYS LTD. (GB) | 1981-07-21 | — | — | US | disclosed |
| US-4255440-A | ANTIALLERGENS, ANTIULCER AGENTS | ALLEN & HANBURYS LIMITED (GB) | 1981-03-10 | — | — | US | disclosed |
| US-4169855-A | ANTIHISTAMINES, ANTISECRETORY AGENTS | Allen & Hansbury, Limited (GB) | 1979-10-02 | — | — | US | disclosed |
| US-4128658-A | HISTAMINE ANTAGONISTS | ALLEN & HANBURYS LIMITED (GB) | 1978-12-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130303791-A1 | PREPARATION OF AMINOMETHYL FURANS AND ALKOXYMETHYL FURAN DERIVATIVES FROM CARBOHYDRATES | DERA, HRH3, HRH4 | CD274 2799/4885SOS1 3960/4885CYP2A6 1764/4885 |
| US-20180057949-A1 | ELECTROCHEMICAL REDUCTIVE AMINATION OF FURFURAL-BASED MOLECULES | BLVRB, GFPT1, DCXR | CD274 3037/4885SOS1 4516/4885CYP2A6 1191/4885 |
| US-10392715-B2 | Electrochemical reductive amination of furfural-based molecules | BLVRB, GFPT1, DCXR | CD274 3037/4885SOS1 4516/4885CYP2A6 1191/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.