SCHEMBL17339062

SCHEMBL17339062

Cc1cc(C(=O)O)n2ccccc12

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FNTA P49354 4/20 0.51
FNTB P49356 4/20 0.51
BAZ2B Q9UIF8 9/20 0.47
BAZ2A Q9UIF9 9/20 0.47
MCL1 Q07820 1/20 0.46
BRD4 O60885 2/20 0.44
BRD9 Q9H8M2 2/20 0.44
BRD2 P25440 1/20 0.44
BRD3 Q15059 1/20 0.44
DAO P14920 1/20 0.43
MAPT P10636 2/20 0.43
THRB P10828 1/20 0.43
KDM4E B2RXH2 2/20 0.41
GLA P06280 1/20 0.41
ATM Q13315 1/20 0.41
RXFP1 Q9HBX9 1/20 0.41
ALDH1A1 P00352 1/20 0.41
TSHR P16473 1/20 0.41
RAB9A P51151 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7439300 0.86 BAZ2B (0.64) FNTAFNTBBAZ2BBAZ2ABRD4
SCHEMBL7449672 0.84 BAZ2B (0.46) FNTAFNTBBAZ2BBAZ2ABRD4
SCHEMBL17339106 0.79 FNTA (0.60) FNTAFNTBBAZ2BBAZ2ABRD4
SCHEMBL17339103 0.79 BAZ2B (0.49) FNTAFNTBBAZ2BBAZ2AMCL1
SCHEMBL17339205 0.79 KDM4E (0.58) FNTAFNTBMAPTKDM4EGLA
SCHEMBL17339178 0.79 FNTA (0.52) FNTAFNTBBAZ2BBAZ2AMCL1
SCHEMBL1289910 0.78 KDM4E (0.54) FNTAFNTBKDM4EGLARXFP1
SCHEMBL30467874 0.77 BAZ2B (0.43) FNTAFNTBBAZ2BBAZ2ABRD4
SCHEMBL17339134 0.75 FNTA (0.48) FNTAFNTBBAZ2BBAZ2AMCL1
SCHEMBL6221151 0.74 FNTA (0.50) FNTAFNTBMAPTKDM4EGLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015188777-A1 CERTAIN PROTEIN KINASE INHIBITORS SHANGHAI FOCHON PHARMACEUTICAL CO LTD (CN) 2015-12-17 WO disclosed