Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 5/20 | 0.60 |
| ▸ | FNTB | P49356 | 5/20 | 0.60 |
| ▸ | MAPT | P10636 | 4/20 | 0.57 |
| ▸ | THRB | P10828 | 1/20 | 0.57 |
| ▸ | TP53 | P04637 | 3/20 | 0.54 |
| ▸ | BAZ2B | Q9UIF8 | 9/20 | 0.53 |
| ▸ | BAZ2A | Q9UIF9 | 9/20 | 0.53 |
| ▸ | BRD4 | O60885 | 2/20 | 0.49 |
| ▸ | BRD9 | Q9H8M2 | 2/20 | 0.49 |
| ▸ | BRD2 | P25440 | 1/20 | 0.49 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29412239 | 0.90 | MAPT (0.68) | FNTAFNTBMAPTTHRBTP53 | |
| SCHEMBL9531095 | 0.87 | FNTA (0.69) | FNTAFNTBMAPTTHRBTP53 | |
| SCHEMBL17339062 | 0.79 | FNTA (0.51) | FNTAFNTBMAPTTHRBTP53 | |
| SCHEMBL17339148 | 0.79 | ALDH1A1 (0.61) | FNTAFNTBMAPTTHRBTP53 | |
| SCHEMBL18549629 | 0.79 | MAPT (0.50) | FNTAFNTBMAPTTHRBTP53 | |
| SCHEMBL28448668 | 0.78 | MAPT (0.48) | FNTAFNTBMAPTTHRBTP53 | |
| SCHEMBL17339103 | 0.77 | BAZ2B (0.49) | FNTAFNTBMAPTTP53BAZ2B | |
| SCHEMBL24304134 | 0.76 | TP53 (0.63) | FNTAFNTBMAPTTHRBTP53 | |
| SCHEMBL18549567 | 0.76 | TP53 (0.44) | FNTAFNTBMAPTTHRBTP53 | |
| SCHEMBL17339178 | 0.76 | FNTA (0.52) | FNTAFNTBMAPTBAZ2BBAZ2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015188777-A1 | CERTAIN PROTEIN KINASE INHIBITORS | SHANGHAI FOCHON PHARMACEUTICAL CO LTD (CN) | 2015-12-17 | — | — | WO | disclosed |