SCHEMBL17339178

SCHEMBL17339178

O=C(O)c1cc(Cl)c2ccccn12

nearest known ligand 0.52

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
FNTA P49354 3/20 0.52
FNTB P49356 3/20 0.52
BAZ2B Q9UIF8 9/20 0.47
BAZ2A Q9UIF9 9/20 0.47
BRD4 O60885 2/20 0.44
BRD9 Q9H8M2 2/20 0.44
BRD2 P25440 1/20 0.44
BRD3 Q15059 1/20 0.44
DAO P14920 1/20 0.43
MCL1 Q07820 1/20 0.42
IDO1 P14902 1/20 0.42
CCR2 P41597 2/20 0.41
ALDH1A1 P00352 2/20 0.41
TSHR P16473 1/20 0.41
KDM4E B2RXH2 1/20 0.41
NPC1 O15118 1/20 0.41
MAPT P10636 1/20 0.41
RAB9A P51151 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17339062 0.79 FNTA (0.51) FNTAFNTBBAZ2BBAZ2ABRD4
SCHEMBL17339192 0.77 KDM4E (0.56) FNTAFNTBBAZ2BBAZ2ABRD4
SCHEMBL17339106 0.76 FNTA (0.60) FNTAFNTBBAZ2BBAZ2ABRD4
SCHEMBL17339103 0.76 BAZ2B (0.49) FNTAFNTBBAZ2BBAZ2ABRD4
SCHEMBL17339134 0.75 FNTA (0.48) FNTAFNTBBAZ2BBAZ2ABRD4
SCHEMBL21358703 0.73 FNTA (0.47) FNTAFNTBBAZ2BBAZ2ABRD4
SCHEMBL17912628 0.72 RORC (0.63) FNTAFNTBBAZ2BBAZ2A
SCHEMBL27767830 0.71 FNTA (0.60) FNTAFNTBIDO1ALDH1A1KDM4E
SCHEMBL26302103 0.70 BAZ2B (0.75) FNTAFNTBBAZ2BBAZ2ABRD4
SCHEMBL28793633 0.69 IDO1 (0.50) FNTAFNTBIDO1ALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015188777-A1 CERTAIN PROTEIN KINASE INHIBITORS SHANGHAI FOCHON PHARMACEUTICAL CO LTD (CN) 2015-12-17 WO disclosed