Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NMT1 | P30419 | 8/20 | 0.41 |
| ▸ | GNRHR | P30968 | 1/20 | 0.41 |
| ▸ | MC4R | P32245 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ARG1 | P05089 | 1/20 | 0.38 |
| ▸ | SLC34A1 | Q06495 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12424513 | 0.81 | ACHE (0.41) | GNRHRATML3MBTL1ARG1ALDH1A1 | |
| SCHEMBL17967839 | 0.80 | ARG1 (0.40) | NMT1GNRHRATML3MBTL1ARG1 | |
| SCHEMBL22458899 | 0.78 | GNRHR (0.38) | NMT1GNRHRATML3MBTL1ARG1 | |
| SCHEMBL12384819 | 0.77 | GNRHR (0.37) | NMT1GNRHRATML3MBTL1ARG1 | |
| SCHEMBL22434943 | 0.76 | ARG1 (0.43) | GNRHRATML3MBTL1ARG1SLC34A1 | |
| SCHEMBL16200403 | 0.75 | MC4R (0.41) | NMT1MC4RALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL3318967 | 0.74 | GNRHR (0.40) | GNRHRL3MBTL1ALDH1A1SMN1; SMN2 | |
| SCHEMBL10030552 | 0.73 | GAA (0.56) | MC4RALDH1A1KMT2ALMNA | |
| SCHEMBL22458898 | 0.73 | ARG1 (0.40) | GNRHRATML3MBTL1ARG1ALDH1A1 | |
| SCHEMBL2001193 | 0.70 | SMO (0.65) | SLC34A1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9212147-B2 | Dihydroxy aromatic heterocyclic compound | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2015-12-15 | — | — | US | disclosed |
| US-9212147-B2 | Dihydroxy aromatic heterocyclic compound | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2015-12-15 | — | — | US | disclosed |