Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.70 |
| ▸ | TSHR | P16473 | 1/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.63 |
| ▸ | MEN1 | O00255 | 6/20 | 0.63 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.60 |
| ▸ | CASP6 | P55212 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 3/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.58 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.58 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.56 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9997287 | 0.86 | HSD17B10 (0.67) | ALDH1A1TSHRKMT2AMEN1PTPN5 | |
| SCHEMBL9997703 | 0.85 | ALDH1A1 (0.67) | ALDH1A1TSHRKMT2AMEN1PTPN5 | |
| SCHEMBL3504223 | 0.83 | ALDH1A1 (0.65) | ALDH1A1TSHRKMT2AMEN1PTPN5 | |
| SCHEMBL11222668 | 0.81 | ALDH1A1 (0.75) | ALDH1A1TSHRKMT2AMEN1PTPN5 | |
| SCHEMBL10361762 | 0.81 | MAPT (0.65) | ALDH1A1KMT2AMEN1PTPN5MAPT | |
| SCHEMBL97271 | 0.81 | ALDH1A1 (0.62) | ALDH1A1TSHRKMT2AMEN1PTPN5 | |
| SCHEMBL14309048 | 0.81 | KMT2A (0.66) | ALDH1A1TSHRKMT2AMEN1POLB | |
| SCHEMBL13313580 | 0.81 | ALDH1A1 (0.62) | ALDH1A1TSHRKMT2AMEN1PTPN5 | |
| SCHEMBL18175045 | 0.80 | ALDH1A1 (0.73) | ALDH1A1TSHRKMT2AMEN1PTPN5 | |
| SCHEMBL16366458 | 0.79 | ALDH1A1 (0.75) | ALDH1A1TSHRKMT2AMEN1PTPN5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2955173-A1 | NOVEL 1,2-BIS-SULFONAMIDE DERIVATIVES AS CHEMOKINE RECEPTOR MODULATORS | ALLERGAN, INC. (US) | 2015-12-16 | — | — | EP | disclosed |