Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.75 |
| ▸ | MEN1 | O00255 | 5/20 | 0.75 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.75 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.71 |
| ▸ | GAA | P10253 | 2/20 | 0.68 |
| ▸ | GFER | P55789 | 1/20 | 0.68 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.68 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.67 |
| ▸ | HTT | P42858 | 1/20 | 0.65 |
| ▸ | TSHR | P16473 | 1/20 | 0.63 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.61 |
| ▸ | POLB | P06746 | 2/20 | 0.61 |
| ▸ | USP2 | O75604 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | CASP6 | P55212 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18175045 | 0.89 | ALDH1A1 (0.73) | ALDH1A1MEN1KMT2APTPN5GAA | |
| SCHEMBL7828166 | 0.88 | MCL1 (0.78) | ALDH1A1MEN1KMT2APTPN5GAA | |
| SCHEMBL11222668 | 0.84 | ALDH1A1 (0.75) | ALDH1A1MEN1KMT2APTPN5GAA | |
| SCHEMBL29390524 | 0.83 | ALDH1A1 (0.65) | ALDH1A1MEN1KMT2APTPN5HTT | |
| SCHEMBL15121254 | 0.83 | PTPN5 (1.00) | ALDH1A1MEN1KMT2APTPN5TSHR | |
| SCHEMBL610080 | 0.83 | ALDH1A1 (0.65) | ALDH1A1MEN1KMT2APTPN5HTT | |
| SCHEMBL16471401 | 0.83 | ALDH1A1 (0.65) | ALDH1A1MEN1KMT2APTPN5GAA | |
| SCHEMBL3500413 | 0.83 | ALDH1A1 (0.69) | ALDH1A1MEN1KMT2APTPN5GAA | |
| SCHEMBL5022924 | 0.83 | ALDH1A1 (1.00) | ALDH1A1MEN1KMT2APTPN5GAA | |
| SCHEMBL3717185 | 0.83 | FABP4 (0.63) | ALDH1A1MEN1KMT2AMCL1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014204859-A2 | BCL6 INHIBITORS AS ANTICANCER AGENTS | MELNICK ARI (US) | 2014-12-24 | — | — | WO | disclosed |