Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.73 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.73 |
| ▸ | MEN1 | O00255 | 6/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.69 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | CASP6 | P55212 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | POLB | P06746 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.56 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.55 |
| ▸ | UQCRB | P14927 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3504223 | 0.91 | ALDH1A1 (0.65) | ALDH1A1PTPN5MEN1KMT2ATSHR | |
| SCHEMBL16366458 | 0.89 | ALDH1A1 (0.75) | ALDH1A1PTPN5MEN1KMT2ATSHR | |
| SCHEMBL3500413 | 0.85 | ALDH1A1 (0.69) | ALDH1A1PTPN5MEN1KMT2ATSHR | |
| SCHEMBL29390524 | 0.85 | ALDH1A1 (0.65) | ALDH1A1PTPN5MEN1KMT2ATSHR | |
| SCHEMBL5022924 | 0.85 | ALDH1A1 (1.00) | ALDH1A1PTPN5MEN1KMT2ATSHR | |
| SCHEMBL16471401 | 0.85 | ALDH1A1 (0.65) | ALDH1A1PTPN5MEN1KMT2ATSHR | |
| SCHEMBL610080 | 0.85 | ALDH1A1 (0.65) | ALDH1A1PTPN5MEN1KMT2ATSHR | |
| SCHEMBL15121254 | 0.85 | PTPN5 (1.00) | ALDH1A1PTPN5MEN1KMT2ATSHR | |
| SCHEMBL9997703 | 0.84 | ALDH1A1 (0.67) | ALDH1A1PTPN5MEN1KMT2ATSHR | |
| SCHEMBL31681331 | 0.83 | ALDH1A1 (0.81) | ALDH1A1PTPN5MEN1KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3085367-A2 | COMPOSITIONS FOR THE DIAGNOSIS, TREATMENT, AND PREVENTION OF AMYOTROPHIC LATERAL SCLEROSIS AND RELATED | Brandeis University (US) | 2016-10-26 | — | — | EP | disclosed |