SCHEMBL17341376

SCHEMBL17341376

c1ccc2c(c1)-c1cccc3c(-c4ccc(-n5c6ccccc6c6ccc7sc8ccccc8c7c65)cc4)ccc-2c13

nearest known ligand 0.32

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ MAPK14 Q16539 1/20 0.32
▸ KDM4E B2RXH2 1/20 0.32
▸ ATM Q13315 1/20 0.32
▸ L3MBTL1 Q9Y468 1/20 0.32
▸ F9 P00740 1/20 0.31
▸ DUSP3 P51452 1/20 0.31
▸ BRDT Q58F21 1/20 0.30
▸ CRHBP P24387 1/20 0.30
▸ CRHR2 Q13324 1/20 0.30
▸ KEAP1 Q14145 1/20 0.30
▸ NFE2L2 Q16236 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17341367 0.91 ALOX5 (0.31) BRDT
SCHEMBL17341677 0.90 S1PR5 (0.34) —
SCHEMBL17341373 0.89 F9 (0.32) MAPK14KDM4EATML3MBTL1F9
SCHEMBL19729774 0.87 KDM4E (0.36) MAPK14KDM4EATML3MBTL1F9
SCHEMBL10014559 0.87 ATM (0.40) KDM4EATML3MBTL1DUSP3
SCHEMBL18777251 0.87 ATM (0.40) KDM4EATML3MBTL1DUSP3
SCHEMBL17341623 0.86 ALOX5 (0.36) MAPK14CRHBPCRHR2KEAP1NFE2L2
SCHEMBL17341272 0.86 ALOX5 (0.38) MAPK14KDM4EATML3MBTL1F9
SCHEMBL17341370 0.86 BRDT (0.32) BRDT
SCHEMBL17341394 0.86 ALDH1A1 (0.31) ATML3MBTL1BRDT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150364692-A1 COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, ORGANIC ELECTROLUMINESCENT ELEMENT, AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2015-12-17 — — US disclosed
US-20150364692-A1 COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, ORGANIC ELECTROLUMINESCENT ELEMENT, AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2015-12-17 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150364692-A1 COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, ORGANIC ELECTROLUMINESCENT ELEMENT, AND ELECTRONIC DEVICE LEF1, EZH1, EPCAM MAPK14 1378/4885KDM4E 2383/4885ATM 2870/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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