Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.42 |
| ▸ | NPC1 | O15118 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | AURKA | O14965 | 1/20 | 0.40 |
| ▸ | TPX2 | Q9ULW0 | 1/20 | 0.40 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.40 |
| ▸ | CDK1 | P06493 | 1/20 | 0.40 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.40 |
| ▸ | GSK3A | P49840 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.40 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.40 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | GCGR | P47871 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 2/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7683073 | 0.83 | SMN1; SMN2 (0.51) | RAB9ANPC1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL15882405 | 0.80 | GCGR (0.57) | RAB9ANPC1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL7692061 | 0.69 | CSNK1A1 (0.82) | RAB9ANPC1KDM4ECCNB2CDK1 | |
| SCHEMBL353039 | 0.68 | BRPF1 (0.44) | NPC1KDM4EHPGDNOTUMSMN1; SMN2 | |
| SCHEMBL10886306 | 0.66 | SLC6A4 (0.50) | RAB9ANPC1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL17342916 | 0.66 | RAB9A (0.41) | RAB9ANPC1KDM4EHPGDAURKA | |
| SCHEMBL280180 | 0.66 | PBRM1 (0.47) | KDM4ESMN1; SMN2MAPTBRPF1NR4A2 | |
| SCHEMBL7689425 | 0.65 | BRPF1 (0.42) | RAB9ANPC1KDM4EHPGDNOTUM | |
| SCHEMBL11451804 | 0.65 | SMN1; SMN2 (0.50) | RAB9ANPC1KDM4ECCNB2CDK1 | |
| SCHEMBL8780719 | 0.65 | AURKA (0.50) | RAB9ANPC1AURKATPX2GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9617211-B2 | Pyrrole derivatives as alpha 7 nAChR modulators | LUPIN LIMITED (IN) | 2017-04-11 | — | — | US | disclosed |
| US-20150361041-A1 | Pyrrole Derivatives as Alpha 7 NACHR Modulators | LUPIN LIMITED (IN) | 2015-12-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150361041-A1 | Pyrrole Derivatives as Alpha 7 NACHR Modulators | CHRM1, CHRNA7, CHRM2 | RAB9A 906/4885NPC1 3243/4885KDM4E 1917/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.