SCHEMBL17343151

SCHEMBL17343151

Cc1ccc(C)c(-c2nccc3c2ccc2c4ccccc4ccc32)c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.46
CYP3A4 P08684 2/20 0.46
MAPK1 P28482 2/20 0.46
LMNA P02545 1/20 0.46
APEX1 P27695 1/20 0.46
PMP22 Q01453 1/20 0.46
MAOA P21397 1/20 0.40
CYP1A2 P05177 6/20 0.40
CYP2A6 P11509 4/20 0.40
BCHE P06276 2/20 0.40
HPRT1 P00492 1/20 0.40
CCR1 P32246 1/20 0.39
CCR5 P51681 1/20 0.39
CCR8 P51685 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
TSHR P16473 1/20 0.39
ALDH1A1 P00352 4/20 0.38
LCK P06239 1/20 0.38
FYN P06241 1/20 0.38
ADORA3 P0DMS8 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18201963 0.89 MAPT (0.46) MAPTCYP3A4MAPK1LMNAAPEX1
SCHEMBL18753201 0.88 CYP2A6 (0.49) MAPTCYP3A4MAPK1MAOACYP1A2
SCHEMBL17343655 0.86 MAPT (0.44) MAPTCYP3A4MAPK1LMNAAPEX1
SCHEMBL13863592 0.85 CYP3A4 (0.49) MAPTCYP3A4MAPK1LMNAAPEX1
SCHEMBL17343149 0.85 CYP3A4 (0.51) MAPTCYP3A4MAPK1LMNAAPEX1
SCHEMBL25849114 0.85 CYP3A4 (0.51) MAPTCYP3A4MAPK1LMNAAPEX1
SCHEMBL13863594 0.85 MAPT (0.43) MAPTCYP3A4MAPK1LMNAAPEX1
SCHEMBL25776415 0.84 CYP3A4 (0.45) MAPTCYP3A4MAPK1LMNAAPEX1
SCHEMBL13863890 0.83 MAOA (0.42) MAPTCYP3A4MAPK1LMNAAPEX1
SCHEMBL14483988 0.82 CYP2A6 (0.43) MAPTLMNACYP1A2CYP2A6BCHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9601704-B2 Organic light-emitting device and display apparatus CANON KABUSHIKI KAISHA (JP) 2017-03-21 US disclosed
US-20150364702-A1 IRIDIUM COMPLEX AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CANON KABUSHIKI KAISHA (JP) 2015-12-17 US disclosed
US-20150364703-A1 ORGANIC LIGHT-EMITTING DEVICE AND DISPLAY APPARATUS CANON KABUSHIKI KAISHA (JP) 2015-12-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150364702-A1 IRIDIUM COMPLEX AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME MAP1LC3C, MAP1LC3B, MAP1LC3A MAPT 1353/4885CYP3A4 304/4885MAPK1 2023/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.