Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | LTA4H | P09960 | 4/20 | 0.46 |
| ▸ | MME | P08473 | 2/20 | 0.45 |
| ▸ | ANPEP | P15144 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | CTSL | P07711 | 1/20 | 0.44 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | ACE | P12821 | 1/20 | 0.42 |
| ▸ | CCKBR | P32239 | 3/20 | 0.42 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.42 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.42 |
| ▸ | ECE1 | P42892 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22301197 | 1.00 | ALDH1A1 (0.51) | ALDH1A1MEN1HPGDKMT2ALTA4H | |
| SCHEMBL17347888 | 0.97 | ALDH1A1 (0.52) | ALDH1A1MEN1HPGDKMT2ALTA4H | |
| SCHEMBL22300838 | 0.95 | MEN1 (0.47) | ALDH1A1MEN1HPGDKMT2ALTA4H | |
| SCHEMBL23463536 | 0.93 | MEN1 (0.48) | ALDH1A1MEN1HPGDKMT2ALTA4H | |
| SCHEMBL24084035 | 0.92 | MEN1 (0.50) | ALDH1A1MEN1HPGDKMT2ALTA4H | |
| SCHEMBL22300839 | 0.90 | MEN1 (0.46) | ALDH1A1MEN1HPGDKMT2ALTA4H | |
| SCHEMBL22193431 | 0.90 | KMT2A (0.51) | ALDH1A1MEN1HPGDKMT2ALTA4H | |
| SCHEMBL24235783 | 0.90 | KMT2A (0.51) | ALDH1A1MEN1HPGDKMT2ALTA4H | |
| SCHEMBL24235730 | 0.90 | ALDH1A1 (0.43) | ALDH1A1MEN1HPGDKMT2ALTA4H | |
| SCHEMBL8724141 | 0.89 | MEN1 (0.49) | ALDH1A1MEN1HPGDKMT2ACTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9700633-B2 | Conjugates of water soluble polymer-amino acid oligopeptide-drug, preparation method and use thereof | JENKEM TECHNOLOGY CO., LTD., TIANJIN BRANCH (CN) | 2017-07-11 | — | — | US | disclosed |
| US-9700633-B2 | Conjugates of water soluble polymer-amino acid oligopeptide-drug, preparation method and use thereof | JENKEM TECHNOLOGY CO., LTD., TIANJIN BRANCH (CN) | 2017-07-11 | — | — | US | disclosed |
| US-20150359900-A1 | CONJUGATES OF WATER SOLUBLE POLYMER-AMINO ACID OLIGOPEPTIDE-DRUG, PREPARATION METHOD AND USE THEREOF | JENKEM TECHNOLOGY CO. LTD., TIANJIN BRANCH (CN) | 2015-12-17 | — | — | US | disclosed |
| US-20150359900-A1 | CONJUGATES OF WATER SOLUBLE POLYMER-AMINO ACID OLIGOPEPTIDE-DRUG, PREPARATION METHOD AND USE THEREOF | JENKEM TECHNOLOGY CO. LTD., TIANJIN BRANCH (CN) | 2015-12-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150359900-A1 | CONJUGATES OF WATER SOLUBLE POLYMER-AMINO ACID OLIGOPEPTIDE-DRUG, PREPARATION METHOD AND USE THEREOF | SLC7A1, NPPA, PEPD | ALDH1A1 2543/4885MEN1 2336/4885HPGD 2713/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.