Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | CTSK | P43235 | 6/20 | 0.49 |
| ▸ | IL1RN | P18510 | 3/20 | 0.47 |
| ▸ | ERAP2 | Q6P179 | 3/20 | 0.47 |
| ▸ | ERAP1 | Q9NZ08 | 3/20 | 0.47 |
| ▸ | CTSS | P25774 | 2/20 | 0.47 |
| ▸ | CTSB | P07858 | 2/20 | 0.47 |
| ▸ | CTSL | P07711 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17446739 | 0.94 | ALDH1A1 (0.48) | MEN1ALDH1A1HPGDKMT2ACTSK | |
| SCHEMBL30480138 | 0.91 | CTSK (0.52) | MEN1ALDH1A1HPGDKMT2ACTSK | |
| SCHEMBL17344012 | 0.89 | ALDH1A1 (0.51) | MEN1ALDH1A1HPGDKMT2ACTSL | |
| SCHEMBL22301197 | 0.89 | ALDH1A1 (0.51) | MEN1ALDH1A1HPGDKMT2ACTSL | |
| SCHEMBL8851532 | 0.88 | ALDH1A1 (0.53) | MEN1ALDH1A1HPGDKMT2ACTSK | |
| SCHEMBL8851538 | 0.88 | ALDH1A1 (0.53) | MEN1ALDH1A1HPGDKMT2ACTSK | |
| SCHEMBL8726503 | 0.88 | ALDH1A1 (0.53) | MEN1ALDH1A1HPGDKMT2ACTSK | |
| SCHEMBL27824395 | 0.88 | CTSK (0.58) | CTSKCTSSCTSBCTSL | |
| SCHEMBL11209394 | 0.88 | CTSK (0.58) | CTSKCTSSCTSBCTSL | |
| SCHEMBL17347888 | 0.87 | ALDH1A1 (0.52) | MEN1ALDH1A1HPGDKMT2ACTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998035982-A1 | COMPOUNDS FOR USE IN ADEPT | ZENECA LIMITED (GB) | 1998-08-20 | — | — | WO | disclosed |