SCHEMBL17345960

SCHEMBL17345960

CSCCNCCN(C)C

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C9 P11712 1/20 0.52
CYP2C19 P33261 1/20 0.52
PRMT3 O60678 1/20 0.42
CARM1 Q86X55 1/20 0.42
PRMT6 Q96LA8 1/20 0.42
PRMT1 Q99873 1/20 0.42
PRMT8 Q9NR22 1/20 0.42
TDP1 Q9NUW8 1/20 0.38
SIGMAR1 Q99720 1/20 0.35
ALDH1A1 P00352 2/20 0.34
ANPEP P15144 1/20 0.34
MAPT P10636 1/20 0.33
CA1 P00915 2/20 0.32
CA2 P00918 2/20 0.32
CA12 O43570 1/20 0.32
CA9 Q16790 1/20 0.32
HTR1A P08908 1/20 0.32
DRD2 P14416 1/20 0.32
HTR2A P28223 1/20 0.32
HTR7 P34969 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17345964 0.86 CYP2C9 (0.54) CYP2C9CYP2C19PRMT3CARM1PRMT6
SCHEMBL948604 0.81
SCHEMBL344526 0.81 CYP2C9 (0.72) CYP2C9CYP2C19PRMT3CARM1PRMT6
SCHEMBL17346286 0.79 CYP2C9 (0.32) CYP2C9CYP2C19ALDH1A1
SCHEMBL18160823 0.78 CYP2C9 (0.50) CYP2C9CYP2C19PRMT3CARM1PRMT6
SCHEMBL65120 0.78 CYP2C19 (0.68) CYP2C9CYP2C19PRMT3CARM1PRMT6
SCHEMBL347138 0.78 CYP2C19 (0.68) CYP2C9CYP2C19PRMT3CARM1PRMT6
Bromide SCHEMBL38656355 0.78 CYP2C9 (0.68) CYP2C9CYP2C19PRMT3CARM1PRMT6
SCHEMBL17346322 0.78 CYP2C9 (0.31) CYP2C9CYP2C19ALDH1A1
SCHEMBL17346275 0.78 CYP2C9 (0.31) CYP2C9CYP2C19ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10550139-B2 Polydentate ligands and their complexes for molecular catalysis TRIAD NATIONAL SECURITY, LLC (US) 2020-02-04 US disclosed
US-20170088571-A1 POLYDENTATE LIGANDS AND THEIR COMPLEXES FOR MOLECULAR CATALYSIS TRIAD NATIONAL SECURITY, LLC 2017-03-30 US disclosed
US-20170088571-A1 POLYDENTATE LIGANDS AND THEIR COMPLEXES FOR MOLECULAR CATALYSIS TRIAD NATIONAL SECURITY, LLC 2017-03-30 US disclosed
WO-2015191505-A1 POLYDENTATE LIGANDS AND THEIR COMPLEXES FOR MOLECULAR CATALYSIS LOS ALAMOS NATIONAL SECURITY, LLC (US) 2015-12-17 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170088571-A1 POLYDENTATE LIGANDS AND THEIR COMPLEXES FOR MOLECULAR CATALYSIS NANS, NCL, NCLN CYP2C9 3796/4885CYP2C19 4732/4885PRMT3 1959/4885
US-10550139-B2 Polydentate ligands and their complexes for molecular catalysis NANS, NCL, NCLN CYP2C9 3796/4885CYP2C19 4732/4885PRMT3 1959/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.