SCHEMBL17346229

SCHEMBL17346229

CCN(CCNCCSC)Cc1ccccc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 4/20 0.43
APP P05067 3/20 0.43
KDM4E B2RXH2 1/20 0.42
CNR2 P34972 1/20 0.41
TSHR P16473 1/20 0.41
MAPK1 P28482 1/20 0.41
BCHE P06276 3/20 0.41
ACHE P22303 3/20 0.41
OPRM1 P35372 2/20 0.40
CYP1A2 P05177 1/20 0.40
CYP2D6 P10635 1/20 0.40
CYP2C9 P11712 1/20 0.40
CYP2C19 P33261 1/20 0.40
MEN1 O00255 1/20 0.40
OPRK1 P41145 1/20 0.40
CHRM2 P08172 1/20 0.40
HTR1A P08908 1/20 0.40
ADRA2A P08913 1/20 0.40
CHRM1 P11229 1/20 0.40
DRD1 P21728 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17346092 0.92 REN (0.43) CNR2TSHRKCNH2
SCHEMBL17346147 0.90 HRH3 (0.45) CNR2TSHRBCHE
SCHEMBL17346246 0.87 MAPT (0.45) BCHEMEN1KCNH2
SCHEMBL17346368 0.85 MAOB (0.42) MAOBAPPKDM4ECNR2TSHR
SCHEMBL8079472 0.82 MAOB (0.49) MAOBAPPKDM4ECNR2TSHR
SCHEMBL17346303 0.81 CARM1 (0.50) MAOBAPPTSHR
SCHEMBL2538898 0.81 MEN1 (0.53) MAOBAPPKDM4ECNR2TSHR
SCHEMBL17346025 0.80 DRD3 (0.47) MAOBAPPBCHEACHEOPRM1
SCHEMBL8113477 0.79 MAOB (0.47) MAOBAPPKDM4EBCHEACHE
SCHEMBL17346281 0.78 PAOX (0.35) CYP2C9CYP2C19MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10550139-B2 Polydentate ligands and their complexes for molecular catalysis TRIAD NATIONAL SECURITY, LLC (US) 2020-02-04 US disclosed
US-20170088571-A1 POLYDENTATE LIGANDS AND THEIR COMPLEXES FOR MOLECULAR CATALYSIS TRIAD NATIONAL SECURITY, LLC 2017-03-30 US disclosed
US-20170088571-A1 POLYDENTATE LIGANDS AND THEIR COMPLEXES FOR MOLECULAR CATALYSIS TRIAD NATIONAL SECURITY, LLC 2017-03-30 US disclosed
WO-2015191505-A1 POLYDENTATE LIGANDS AND THEIR COMPLEXES FOR MOLECULAR CATALYSIS LOS ALAMOS NATIONAL SECURITY, LLC (US) 2015-12-17 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170088571-A1 POLYDENTATE LIGANDS AND THEIR COMPLEXES FOR MOLECULAR CATALYSIS NANS, NCL, NCLN MAOB 3256/4885APP 3054/4885KDM4E 4854/4885
US-10550139-B2 Polydentate ligands and their complexes for molecular catalysis NANS, NCL, NCLN MAOB 3256/4885APP 3054/4885KDM4E 4854/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.