SCHEMBL17346347

SCHEMBL17346347

CN(C)CCCN(CCSCc1ccccc1)Cc1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 2/20 0.47
ALDH1A1 P00352 2/20 0.45
SIGMAR1 Q99720 1/20 0.44
TSHR P16473 1/20 0.43
CALM1 P0DP23 1/20 0.43
CAMKK2 Q96RR4 1/20 0.43
TAAR1 Q96RJ0 1/20 0.41
HTR2A P28223 1/20 0.40
HRH1 P35367 1/20 0.40
NPY2R P49146 1/20 0.39
CYP2C19 P33261 2/20 0.39
KDM4E B2RXH2 2/20 0.39
LMNA P02545 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
GAA P10253 1/20 0.39
CYP1A2 P05177 1/20 0.38
CYP3A4 P08684 1/20 0.38
CYP2D6 P10635 1/20 0.38
CYP2C9 P11712 1/20 0.38
MGLL Q99685 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17346204 0.94 HTT (0.47) HTTALDH1A1SIGMAR1TSHRCALM1
SCHEMBL17346348 0.87 BCHE (0.41) HTTALDH1A1SIGMAR1MGLL
SCHEMBL17346351 0.87 BCHE (0.55) HTTSIGMAR1CALM1CAMKK2
SCHEMBL17346300 0.84 CYP2C19 (0.46) HTTALDH1A1TSHRCALM1CAMKK2
SCHEMBL17346288 0.83 CARM1 (0.49) ALDH1A1SIGMAR1TSHRCALM1CAMKK2
SCHEMBL17345900 0.83 SIGMAR1 (0.47) ALDH1A1SIGMAR1TAAR1HTR2AHRH1
SCHEMBL17346327 0.82 HTT (0.47) HTTALDH1A1SIGMAR1TSHRCALM1
SCHEMBL24244319 0.82 TAAR1 (0.54) HTTALDH1A1SIGMAR1TSHRTAAR1
SCHEMBL10039137 0.82 ALDH1A1 (0.58) HTTALDH1A1SIGMAR1TSHRCALM1
SCHEMBL17346219 0.81 HTT (0.49) HTTALDH1A1SIGMAR1TSHRCALM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10550139-B2 Polydentate ligands and their complexes for molecular catalysis TRIAD NATIONAL SECURITY, LLC (US) 2020-02-04 US disclosed
US-20170088571-A1 POLYDENTATE LIGANDS AND THEIR COMPLEXES FOR MOLECULAR CATALYSIS TRIAD NATIONAL SECURITY, LLC 2017-03-30 US disclosed
US-20170088571-A1 POLYDENTATE LIGANDS AND THEIR COMPLEXES FOR MOLECULAR CATALYSIS TRIAD NATIONAL SECURITY, LLC 2017-03-30 US disclosed
WO-2015191505-A1 POLYDENTATE LIGANDS AND THEIR COMPLEXES FOR MOLECULAR CATALYSIS LOS ALAMOS NATIONAL SECURITY, LLC (US) 2015-12-17 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170088571-A1 POLYDENTATE LIGANDS AND THEIR COMPLEXES FOR MOLECULAR CATALYSIS NANS, NCL, NCLN HTT 3387/4885ALDH1A1 862/4885SIGMAR1 412/4885
US-10550139-B2 Polydentate ligands and their complexes for molecular catalysis NANS, NCL, NCLN HTT 3387/4885ALDH1A1 862/4885SIGMAR1 412/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.