SCHEMBL1734653

SCHEMBL1734653

CCCCCCCCCCCCCCCCCCOC(OC(OCCCCCCCCCCCCCCCCCC)C(OCCCCCCCCCCCCCCCC)OCCCCCCCCCCCCCCCC)C(OCCCCCCCCCCCCCCCC)OCCCCCCCCCCCCCCCC

nearest known ligand 0.50

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
DNM1 Q05193 3/20 0.50
THRB P10828 2/20 0.40
TSHR P16473 1/20 0.40
MEN1 O00255 1/20 0.38
HTT P42858 1/20 0.38
KMT2A Q03164 1/20 0.38
MAPT P10636 1/20 0.38
LPAR1 Q92633 4/20 0.38
LPAR3 Q9UBY5 4/20 0.38
LPAR2 Q9HBW0 1/20 0.38
USP2 O75604 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7591315 0.89 DNM1 (0.52) DNM1THRBTSHRMEN1HTT
SCHEMBL9393419 0.81 ADRB2 (0.45) DNM1THRBTSHR
SCHEMBL8843029 0.80 DNM1 (0.50) DNM1THRBTSHRMEN1HTT
SCHEMBL7791336 0.80 DNM1 (0.50) DNM1THRBTSHRMEN1HTT
SCHEMBL9714750 0.78 DNM1 (0.48) DNM1THRBTSHRMEN1HTT
SCHEMBL9714692 0.78 DNM1 (0.48) DNM1THRBTSHRMEN1HTT
SCHEMBL9546960 0.76 DNM1 (0.47) DNM1THRBMEN1HTTKMT2A
SCHEMBL30535779 0.76 DNM1 (0.47) DNM1THRBMEN1HTTKMT2A
SCHEMBL3147596 0.76 DNM1 (0.47) DNM1THRBMEN1HTTKMT2A
SCHEMBL28329768 0.76 DNM1 (0.47) DNM1THRBMEN1HTTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1778363-B1 STABLE GEL-FORMULATION WITH INCREASED ELECTROLYTE CONCENTRATION HENKEL AG & CO KGAA (DE) 2012-08-01 EP claimed
EP-1986590-B1 RHEOPEXY GELS AS VEHICLES HENKEL AG & CO KGAA (DE) 2011-11-16 EP claimed
WO-2011131915-A2 DEVICE FOR SHUTTING OFF A CONTROL SYSTEM BAY WITH PROXIMITY SENSOR NAVAG (FR) 2011-10-27 WO claimed
EP-1035825-B2 HAIR COLORANT PREPARATION HENKEL AG & CO KGAA (DE) 2008-09-24 EP claimed
EP-1035825-B1 HAIR COLORANT PREPARATION HENKEL KGAA (DE) 2002-09-25 EP claimed