Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | LPAR1 | Q92633 | 4/20 | 0.38 |
| ▸ | LPAR3 | Q9UBY5 | 4/20 | 0.38 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8843029 | 1.00 | DNM1 (0.50) | DNM1THRBTSHRMEN1HTT | |
| SCHEMBL7791270 | 0.90 | ADRB2 (0.39) | DNM1TSHR | |
| SCHEMBL7591315 | 0.84 | DNM1 (0.52) | DNM1THRBTSHRMEN1HTT | |
| SCHEMBL30535779 | 0.81 | DNM1 (0.47) | DNM1THRBMEN1HTTKMT2A | |
| SCHEMBL28329768 | 0.81 | DNM1 (0.47) | DNM1THRBMEN1HTTKMT2A | |
| SCHEMBL4312227 | 0.81 | DNM1 (0.47) | DNM1THRBMEN1HTTKMT2A | |
| SCHEMBL3147596 | 0.81 | DNM1 (0.47) | DNM1THRBMEN1HTTKMT2A | |
| SCHEMBL9546960 | 0.81 | DNM1 (0.47) | DNM1THRBMEN1HTTKMT2A | |
| SCHEMBL28027780 | 0.81 | DNM1 (0.42) | DNM1HTTLPAR1LPAR3LPAR2 | |
| SCHEMBL1734653 | 0.80 | DNM1 (0.50) | DNM1THRBTSHRMEN1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0512501-B1 | Use of acetals | CLARIANT GMBH (DE) | 2001-11-28 | — | — | EP | disclosed |
| EP-0537687-B1 | Biodegradable fiber treating agent | HOECHST AG (DE) | 1997-03-12 | — | — | EP | disclosed |
| EP-0537687-A1 | Biodegradable fiber treating agent | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-04-21 | — | — | EP | disclosed |
| EP-0512501-A2 | Use of acetals | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-11-11 | — | — | EP | disclosed |