SCHEMBL17347755

SCHEMBL17347755

CCCC(=O)N[C@H]1Cc2cc(O)cc(C(=O)OCOC(=O)C(C)(C)C)c2OB1O

nearest known ligand 0.34

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ PRKCB P05771 1/20 0.32
▸ PRKCA P17252 1/20 0.32
▸ PRKCH P24723 1/20 0.32
▸ PRKCE Q02156 1/20 0.32
▸ PRKCD Q05655 1/20 0.32
▸ MTNR1A P48039 1/20 0.30
▸ MTNR1B P49286 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23130196 1.00 PRKCB (0.32) PRKCBPRKCAPRKCHPRKCEPRKCD
SCHEMBL23129656 0.93 PRKCB (0.32) PRKCBPRKCAPRKCHPRKCEPRKCD
SCHEMBL17347685 0.93 PRKCB (0.32) PRKCBPRKCAPRKCHPRKCEPRKCD
SCHEMBL17347692 0.92 MTNR1A (0.30) MTNR1AMTNR1B
SCHEMBL17347711 0.90 PARP1 (0.30) MTNR1AMTNR1B
SCHEMBL23129964 0.90 PARP1 (0.30) MTNR1AMTNR1B
SCHEMBL23129891 0.90 MTNR1A (0.32) MTNR1AMTNR1B
SCHEMBL17347827 0.90 MTNR1A (0.32) MTNR1AMTNR1B
SCHEMBL17347816 0.89 PRKCB (0.33) PRKCBPRKCAPRKCHPRKCEPRKCD
SCHEMBL23129714 0.89 PRKCB (0.33) PRKCBPRKCAPRKCHPRKCEPRKCD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3882252-A1 BETA-LACTAMASE INHIBITORS Venatorx Pharmaceuticals, Inc. (US) 2021-09-22 — — EP disclosed
US-11008346-B2 Beta-lactamase inhibitors VenatoRx Pharmaceuticals, Inc. (US) 2021-05-18 — — US disclosed
EP-3154989-B1 BETA-LACTAMASE INHIBITORS VENATORX PHARMACEUTICALS INC (US) 2021-03-24 — — EP disclosed
US-20200361962-A1 BETA-LACTAMASE INHIBITORS NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2020-11-19 — — US disclosed
US-9926336-B2 Beta-lactamase inhibitors VENATORX PHARMACEUTICALS (US) 2018-03-27 — — US disclosed
US-20170342092-A1 BETA-LACTAMASE INHIBITORS NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2017-11-30 — — US disclosed
US-9783555-B2 Beta-lactamase inhibitors VenatoRx Pharmaceuticals, Inc. (US) 2017-10-10 — — US disclosed
US-20170226135-A1 BETA-LACTAMASE INHIBITORS NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2017-08-10 — — US disclosed
US-9637504-B2 Beta-lactamase inhibitors VenatoRx Pharmaceuticals, Inc. (US) 2017-05-02 — — US disclosed
US-20160264598-A1 BETA-LACTAMASE INHIBITORS NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2016-09-15 — — US disclosed
WO-2015191907-A1 BETA-LACTAMASE INHIBITORS VenatoRx Pharmaceuticals, Inc. (US) 2015-12-17 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11008346-B2 Beta-lactamase inhibitors MGAM, GAA, LCT PRKCB 2479/4885PRKCA 2852/4885PRKCH 2897/4885
US-20170342092-A1 BETA-LACTAMASE INHIBITORS MGAM, GAA, LCT PRKCB 2479/4885PRKCA 2852/4885PRKCH 2897/4885
US-20200361962-A1 BETA-LACTAMASE INHIBITORS MGAM, GAA, LCT PRKCB 2479/4885PRKCA 2852/4885PRKCH 2897/4885
US-20170226135-A1 BETA-LACTAMASE INHIBITORS MGAM, GAA, LCT PRKCB 2479/4885PRKCA 2852/4885PRKCH 2897/4885
US-20160264598-A1 BETA-LACTAMASE INHIBITORS MGAM, GAA, LCT PRKCB 2479/4885PRKCA 2852/4885PRKCH 2897/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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