Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 7/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17337354 | 0.88 | NAMPT (0.42) | NAMPTNPC1ALDH1A1KDM4E | |
| SCHEMBL17337351 | 0.88 | NAMPT (0.42) | NAMPTNPC1ALDH1A1KDM4E | |
| SCHEMBL22667379 | 0.87 | NAMPT (0.39) | NAMPTNPC1ALDH1A1 | |
| SCHEMBL18966488 | 0.82 | MTNR1A (0.41) | KMT2AMEN1 | |
| SCHEMBL18966466 | 0.78 | NAMPT (0.37) | NAMPTALDH1A1GAA | |
| SCHEMBL18966514 | 0.78 | TP53 (0.30) | — | |
| SCHEMBL18966461 | 0.78 | NAMPT (0.37) | NAMPTLMNAALDH1A1 | |
| SCHEMBL18966481 | 0.78 | TAS1R3 (0.32) | LMNAKMT2AMEN1 | |
| SCHEMBL18966571 | 0.77 | MTNR1A (0.31) | LMNAKMT2AMEN1 | |
| SCHEMBL17337093 | 0.76 | KDM4E (0.44) | NAMPTNPC1LMNAALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015191907-A1 | BETA-LACTAMASE INHIBITORS | VenatoRx Pharmaceuticals, Inc. (US) | 2015-12-17 | — | — | WO | disclosed |