Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 3/20 | 0.33 |
| ▸ | HTR2A | P28223 | 3/20 | 0.33 |
| ▸ | DRD3 | P35462 | 3/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.32 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | UCK2 | Q9BZX2 | 1/20 | 0.30 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.30 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.30 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18966467 | 0.95 | MAPT (0.34) | NAMPTDRD2HTR2ADRD3MTNR1A | |
| SCHEMBL18966571 | 0.92 | MTNR1A (0.31) | MTNR1AMTNR1BMAPTLMNAUCK2 | |
| SCHEMBL18966481 | 0.91 | TAS1R3 (0.32) | DRD2MTNR1AMTNR1BMAPTLMNA | |
| SCHEMBL18966514 | 0.87 | TP53 (0.30) | — | |
| SCHEMBL17337165 | 0.86 | NAMPT (0.38) | NAMPTDRD2HTR2ADRD3MAPT | |
| SCHEMBL17337169 | 0.86 | NAMPT (0.38) | NAMPTDRD2HTR2ADRD3MAPT | |
| SCHEMBL18966466 | 0.85 | NAMPT (0.37) | NAMPTDRD3MTNR1AMTNR1BMAPT | |
| SCHEMBL18966488 | 0.85 | MTNR1A (0.41) | MTNR1AMTNR1BMAPT | |
| SCHEMBL18957153 | 0.85 | NAMPT (0.38) | NAMPTDRD2HTR2ADRD3MAPT | |
| SCHEMBL18797980 | 0.85 | NAMPT (0.35) | NAMPTDRD2HTR2ADRD3MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017100537-A1 | BETA-LACTAMASE INHIBITORS | VenatoRx Pharmaceuticals, Inc. (US) | 2017-06-15 | — | — | WO | disclosed |