SCHEMBL1734809

SCHEMBL1734809

C=C(C)C(=O)OCCCCNC(=O)Nc1cc(C)ccc1O

nearest known ligand 0.45

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
POLB P06746 3/20 0.45
KMT2A Q03164 2/20 0.45
GAA P10253 5/20 0.43
KCNMA1 Q12791 4/20 0.41
HTT P42858 3/20 0.40
CA12 O43570 2/20 0.40
CA1 P00915 2/20 0.40
CA2 P00918 2/20 0.40
CA9 Q16790 2/20 0.40
MAPT P10636 2/20 0.40
MAPK1 P28482 1/20 0.40
APEX1 P27695 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
TSHR P16473 2/20 0.39
MEN1 O00255 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3254727 0.92 GAA (0.43) POLBKMT2AGAAKCNMA1HTT
SCHEMBL3249553 0.85 HDAC1 (0.51)
SCHEMBL1735931 0.85 MARS1 (0.46) POLBKMT2AGAAHTTMAPT
SCHEMBL3255301 0.84 GAA (0.45) POLBGAAKCNMA1HTTCA12
SCHEMBL3250159 0.84 POLB (0.45) POLBKMT2AGAAKCNMA1HTT
SCHEMBL1734806 0.80 EPHX2 (0.47) POLBKMT2AGAAHTTMAPT
SCHEMBL3246727 0.79 ALDH1A1 (0.47) POLBKMT2AGAAHTTAPEX1
SCHEMBL7099322 0.78 GAA (0.52) POLBKMT2AGAAKCNMA1HTT
SCHEMBL1737301 0.77 ALDH1A1 (0.44) POLBKMT2AHTTCA12CA1
SCHEMBL7097410 0.77 GAA (0.51) POLBKMT2AGAAKCNMA1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3521927-B1 POSITIVE WORKING LITHOGRAPHIC PRINTING PLATE PRECURSOR, METHOD FOR MANUFACTURING THE PRECURSOR AND METHOD FOR PRODUCING LITHOGRAPHIC PRINTING PLATE FUJIFILM CORP (JP) 2021-10-27 EP disclosed
US-10649337-B2 Positive type lithographic printing plate precursor, method of producing same, and method of preparing lithographic printing plate FUJIFILM CORPORATION (JP) 2020-05-12 US disclosed
EP-3521927-A1 POSITIVE PLANOGRAPHIC PRINTING ORIGINAL PLATE AND METHOD FOR MANUFACTURING SAME, AND METHOD FOR PRODUCING PLANOGRAPHIC PRINTING PLATE FUJIFILM Corporation (JP) 2019-08-07 EP disclosed
US-20190212652-A1 POSITIVE TYPE LITHOGRAPHIC PRINTING PLATE PRECURSOR, METHOD OF PRODUCING SAME, AND METHOD OF PREPARING LITHOGRAPHIC PRINTING PLATE FUJIFILM CORPORATION (JP) 2019-07-11 US disclosed
EP-2538275-B1 PROCESS FOR MAKING LITHOGRAPHIC PRINTING PLATE FUJIFILM CORP (JP) 2014-10-29 EP disclosed
EP-1705004-B1 Planographic printing plate precursor FUJIFILM CORP (JP) 2013-09-25 EP disclosed
US-20130004897-A1 METHOD FOR MANUFACTURING A PLANOGRAPHIC PRINTING PLATE FUJIFILM CORPORATION (JP) 2013-01-03 US disclosed
EP-2538275-A1 PROCESS FOR MAKING LITHOGRAPHIC PRINTING PLATE FUJIFILM Corporation (JP) 2012-12-26 EP disclosed
EP-2251195-B1 Lithographic printing plate precursor FUJIFILM CORP (JP) 2011-11-16 EP disclosed
US-20110265148-A1 SYSTEM AND METHOD FOR CREATING A SECURE TRUSTED SOCIAL NETWORK TAM CHUNG MING 2011-10-27 US disclosed
EP-2251195-A1 Lithographic printing plate precursor Fujifilm Corporation (JP) 2010-11-17 EP disclosed
EP-1136886-B1 Positive-working presensitized plate useful for preparing a lithographic printing plate FUJIFILM CORP (JP) 2010-05-19 EP disclosed
US-20090246693-A1 NEGATIVE-WORKING LITHOGRAPHIC PRINTING PLATE PRECURSOR AND METHOD OF LITHOGRAPHIC PRINTING USING SAME FUJIFILM CORPORATION (JP) 2009-10-01 US disclosed
US-20080182202-A1 Planographic printing plate material and resin used therein KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2008-07-31 US disclosed
EP-1705004-A1 Planographic printing plate precursor FUJI PHOTO FILM CO., LTD. (JP) 2006-09-27 EP disclosed
US-6517987-B2 Mixture of 1,2-naphthoquinone-2-diazide-5-sulfonic acid and polymer FUJI PHOTO FILM CO., LTD. (JP) 2003-02-11 US disclosed
US-20010041299-A1 Positive-working presensitized plate useful for preparing a lithographic printing plate FUJIFILM CORPORATION (JP) 2001-11-15 US disclosed
EP-1136886-A1 Positive-working presensitized plate useful for preparing a lithographic printing plate Fuji Photo Film Co., Ltd. (JP) 2001-09-26 EP disclosed