SCHEMBL1735931

SCHEMBL1735931

C=C(C)C(=O)OCCCCNC(=O)Nc1ccccc1O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MARS1 P56192 1/20 0.46
POLB P06746 2/20 0.44
KMT2A Q03164 2/20 0.43
ALDH1A1 P00352 4/20 0.42
HTT P42858 2/20 0.41
APEX1 P27695 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
HDAC3 O15379 2/20 0.41
HDAC1 Q13547 2/20 0.41
TSHR P16473 2/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
LMNA P02545 1/20 0.40
EPHX1 P07099 3/20 0.39
HDAC4 P56524 1/20 0.39
HDAC7 Q8WUI4 1/20 0.39
HDAC2 Q92769 1/20 0.39
HDAC10 Q969S8 1/20 0.39
HDAC11 Q96DB2 1/20 0.39
HDAC8 Q9BY41 1/20 0.39
HDAC6 Q9UBN7 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3252701 0.91 MARS1 (0.44) MARS1POLBKMT2AALDH1A1HTT
SCHEMBL3246727 0.89 ALDH1A1 (0.47) POLBKMT2AALDH1A1HTTAPEX1
SCHEMBL3249553 0.86 HDAC1 (0.51) HDAC1HDAC2
SCHEMBL1734809 0.85 POLB (0.45) POLBKMT2AHTTAPEX1TDP1
SCHEMBL5705709 0.83 HTR1A (0.41) POLBKMT2AALDH1A1HTTAPEX1
SCHEMBL1735871 0.83 GAA (0.46) MARS1POLBKMT2AALDH1A1HTT
SCHEMBL26662008 0.82 EPHX1 (0.60) POLBKMT2AALDH1A1HTTAPEX1
SCHEMBL3252282 0.81 MARS1 (0.47) MARS1POLBKMT2AALDH1A1TDP1
SCHEMBL1737301 0.80 ALDH1A1 (0.44) POLBKMT2AALDH1A1HTTAPEX1
SCHEMBL26661999 0.80 ALDH1A1 (0.56) POLBKMT2AALDH1A1HTTAPEX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3521927-B1 POSITIVE WORKING LITHOGRAPHIC PRINTING PLATE PRECURSOR, METHOD FOR MANUFACTURING THE PRECURSOR AND METHOD FOR PRODUCING LITHOGRAPHIC PRINTING PLATE FUJIFILM CORP (JP) 2021-10-27 EP disclosed
US-10649337-B2 Positive type lithographic printing plate precursor, method of producing same, and method of preparing lithographic printing plate FUJIFILM CORPORATION (JP) 2020-05-12 US disclosed
EP-3521927-A1 POSITIVE PLANOGRAPHIC PRINTING ORIGINAL PLATE AND METHOD FOR MANUFACTURING SAME, AND METHOD FOR PRODUCING PLANOGRAPHIC PRINTING PLATE FUJIFILM Corporation (JP) 2019-08-07 EP disclosed
US-20190212652-A1 POSITIVE TYPE LITHOGRAPHIC PRINTING PLATE PRECURSOR, METHOD OF PRODUCING SAME, AND METHOD OF PREPARING LITHOGRAPHIC PRINTING PLATE FUJIFILM CORPORATION (JP) 2019-07-11 US disclosed
EP-2538275-B1 PROCESS FOR MAKING LITHOGRAPHIC PRINTING PLATE FUJIFILM CORP (JP) 2014-10-29 EP disclosed
EP-1705004-B1 Planographic printing plate precursor FUJIFILM CORP (JP) 2013-09-25 EP disclosed
US-20130004897-A1 METHOD FOR MANUFACTURING A PLANOGRAPHIC PRINTING PLATE FUJIFILM CORPORATION (JP) 2013-01-03 US disclosed
EP-2538275-A1 PROCESS FOR MAKING LITHOGRAPHIC PRINTING PLATE FUJIFILM Corporation (JP) 2012-12-26 EP disclosed
EP-2251195-B1 Lithographic printing plate precursor FUJIFILM CORP (JP) 2011-11-16 EP disclosed
US-20110265148-A1 SYSTEM AND METHOD FOR CREATING A SECURE TRUSTED SOCIAL NETWORK TAM CHUNG MING 2011-10-27 US disclosed
EP-2251195-A1 Lithographic printing plate precursor Fujifilm Corporation (JP) 2010-11-17 EP disclosed
EP-1136886-B1 Positive-working presensitized plate useful for preparing a lithographic printing plate FUJIFILM CORP (JP) 2010-05-19 EP disclosed
US-20090246693-A1 NEGATIVE-WORKING LITHOGRAPHIC PRINTING PLATE PRECURSOR AND METHOD OF LITHOGRAPHIC PRINTING USING SAME FUJIFILM CORPORATION (JP) 2009-10-01 US disclosed
US-20080182202-A1 Planographic printing plate material and resin used therein KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2008-07-31 US disclosed
EP-1705004-A1 Planographic printing plate precursor FUJI PHOTO FILM CO., LTD. (JP) 2006-09-27 EP disclosed
US-6517987-B2 Mixture of 1,2-naphthoquinone-2-diazide-5-sulfonic acid and polymer FUJI PHOTO FILM CO., LTD. (JP) 2003-02-11 US disclosed
US-20010041299-A1 Positive-working presensitized plate useful for preparing a lithographic printing plate FUJIFILM CORPORATION (JP) 2001-11-15 US disclosed
EP-1136886-A1 Positive-working presensitized plate useful for preparing a lithographic printing plate Fuji Photo Film Co., Ltd. (JP) 2001-09-26 EP disclosed