SCHEMBL1734814

SCHEMBL1734814

COCNC(=O)CCl

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8644277 0.81 TSHR (0.38)
SCHEMBL8639742 0.79 TSHR (0.46)
SCHEMBL227856 0.78
SCHEMBL1965413 0.77
SCHEMBL29114771 0.75
SCHEMBL11505724 0.75 RECQL (0.58)
SCHEMBL14750681 0.75
SCHEMBL6637390 0.75
SCHEMBL13409841 0.75 LDHA (0.38)
SCHEMBL24070642 0.75 TSHR (0.64)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1954287-B2 CETP INHIBITORS MERCK SHARP & DOHME (US) 2016-02-24 EP disclosed
US-8334290-B2 CETP inhibitors MERCK SHARP & DOHME CORP. (US) 2012-12-18 US disclosed
EP-1954287-B1 CETP INHIBITORS MERCK SHARP & DOHME (US) 2011-11-16 EP disclosed
US-20110263898-A1 ETHER-AMIDE COMPOUNDS AND PREPARATION AND USES THEREOF RHODIA OPERATIONS (FR) 2011-10-27 US disclosed
US-20110263898-A1 ETHER-AMIDE COMPOUNDS AND PREPARATION AND USES THEREOF RHODIA OPERATIONS (FR) 2011-10-27 US disclosed
US-20110262658-A1 PROCESS AND DEVICE FOR TREATING THE COATING OF THERMOPLASTIC RESIN CONTAINERS ZOPPAS MATTEO 2011-10-27 US disclosed
US-20100183978-A1 SURFACE-TREATING AGENT FOR PATTERN FORMATION AND PATTERN FORMING METHOD USING THE TREATING AGENT FUJIFILM CORPORATION (JP) 2010-07-22 US disclosed
US-20100183978-A1 SURFACE-TREATING AGENT FOR PATTERN FORMATION AND PATTERN FORMING METHOD USING THE TREATING AGENT FUJIFILM CORPORATION (JP) 2010-07-22 US disclosed
US-20090264405-A1 Cetp Inhibitors MERCK SHARP & DOHME LLC 2009-10-22 US disclosed
EP-1954287-A2 CETP INHIBITORS Merck & Co., Inc. (US) 2008-08-13 EP disclosed
WO-2007070173-A2 CETP INHIBITORS MERCK & CO., INC. (US) 2007-06-21 WO disclosed
EP-0053495-B1 PROCESS FOR PRODUCING N-(HALOMETHYL) ACYLAMIDES MONSANTO COMPANY (US) 1984-08-08 EP disclosed
US-4395546-A DECOLORING EFFLUENTS CIBA-GEIGY CORPORATION (US) 1983-07-26 US disclosed
EP-0053495-A1 Process for producing N-(halomethyl) acylamides MONSANTO COMPANY (US) 1982-06-09 EP disclosed
US-4311858-A Process for producing N-(halomethyl) acyl-amides MONSANTO COMPANY (US) 1982-01-19 US disclosed
US-4306080-A CELLULOSE AMIDE DERIVATIVES USEFUL FOR DECOLORING CIBA-GEIGY CORPORATION (CH) 1981-12-15 US disclosed
US-4178438-A PURIFICATION OF INDUSTRIAL WASTES CIBA-GEIGY AKTIENGESELLSCHAFT (CH) 1979-12-11 US disclosed