Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | HSPA1A | P0DMV8 | 1/20 | 0.56 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.56 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.56 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.54 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | AHR | P35869 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.46 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20490838 | 0.95 | MEN1 (0.53) | MEN1KMT2AHSPA1APABPC1ADORA2A | |
| SCHEMBL1500541 | 0.93 | HSPA1A (0.67) | MEN1KMT2AHSPA1APABPC1ADORA2A | |
| SCHEMBL9453251 | 0.92 | MEN1 (0.50) | MEN1KMT2AHSPA1APABPC1ADORA2A | |
| SCHEMBL9453245 | 0.92 | HSPA1A (0.57) | MEN1KMT2AHSPA1APABPC1ADORA2A | |
| SCHEMBL17187939 | 0.90 | HPGD (0.56) | MEN1KMT2AHSPA1APABPC1ADORA2A | |
| SCHEMBL1736347 | 0.89 | HSPA1A (0.53) | MEN1KMT2AHSPA1APABPC1GRM1 | |
| SCHEMBL16754922 | 0.89 | CA1 (0.50) | MEN1KMT2AHSPA1APABPC1ADORA2A | |
| SCHEMBL2892449 | 0.87 | MEN1 (0.58) | MEN1KMT2AHSPA1APABPC1ADORA2A | |
| SCHEMBL13323538 | 0.87 | KMT2A (0.54) | MEN1KMT2AHSPA1APABPC1ADORA2A | |
| SCHEMBL2890258 | 0.86 | HSPA1A (0.54) | MEN1KMT2AHSPA1APABPC1ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7714095-B2 | Phase transfer catalyzed method for preparation of polyetherimides | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2010-05-11 | — | — | US | claimed |
| US-7481959-B2 | Method for controlling haze in an article comprising a polymer composition | SABIC INNOVATIVE PLASTICS IP B.V. (US) | 2009-01-27 | — | — | US | claimed |
| EP-1989246-A2 | PHASE TRANSFER CATALYZED METHOD FOR PREPARATION OF POLYETHERIMIDES | Sabic Innovative Plastics IP B.V. (NL) | 2008-11-12 | — | — | EP | claimed |
| WO-2007100473-A2 | PHASE TRANSFER CATALYZED METHOD FOR PREPARATION OF POLYETHERIMIDES | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2007-09-07 | — | — | WO | claimed |
| EP-1805265-A1 | METHOD FOR CONTROLLING HAZE IN AN ARTICLE COMPRISING A POLYMER COMPOSITION | General Electric Company (US) | 2007-07-11 | — | — | EP | claimed |
| US-20060173158-A1 | Phase transfer catalyzed method for preparation of polyetherimides | GENERAL ELECTRIC COMPANY (US) | 2006-08-03 | — | — | US | claimed |
| WO-2006039160-A1 | METHOD FOR CONTROLLING HAZE IN AN ARTICLE COMPRISING A POLYMER COMPOSITION | GENERAL ELECTRIC COMPANY (US) | 2006-04-13 | — | — | WO | claimed |
| US-20060066004-A1 | Method for controlling haze in an article comprising a polymer composition | GENERAL ELECTRIC COMPANY | 2006-03-30 | — | — | US | claimed |
| US-6790934-B2 | VIA CATALYTIC POLYMERIZATION IN PRESENCE OF WATER-IMMISCIBLE SOLVENT; EXTRACTION; FILTRATION | GENERAL ELECTRIC COMPANY | 2004-09-14 | — | — | US | claimed |
| US-20020151675-A1 | Method for purification of aromatic polyethers | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2002-10-17 | — | — | US | claimed |
| EP-1233997-A1 | METHOD FOR PURIFICATION OF AROMATIC POLYETHERS | GENERAL ELECTRIC COMPANY (US) | 2002-08-28 | — | — | EP | claimed |
| WO-2001021686-A1 | METHOD FOR PURIFICATION OF AROMATIC POLYETHERS | GENERAL ELECTRIC COMPANY (US) | 2001-03-29 | — | — | WO | claimed |
| EP-3131949-B1 | METHODS OF MANUFACTURE OF POLYETHERIMIDES | SABIC GLOBAL TECHNOLOGIES BV (NL) | 2019-01-30 | — | — | EP | disclosed |
| EP-2162457-B1 | CARBAZOLYL POLYMERS FOR ORGANIC ELECTRONIC DEVICES | BOE TECHNOLOGY GROUP CO LTD (CN) | 2018-08-22 | — | — | EP | disclosed |
| EP-3131949-A1 | METHODS OF MANUFACTURE OF POLYETHERIMIDES | SABIC Global Technologies B.V. (NL) | 2017-02-22 | — | — | EP | disclosed |
| US-20170029567-A1 | METHODS OF MANUFACTURE OF POLYETHERIMIDES | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2017-02-02 | — | — | US | disclosed |
| US-6790934-B2 | VIA CATALYTIC POLYMERIZATION IN PRESENCE OF WATER-IMMISCIBLE SOLVENT; EXTRACTION; FILTRATION | GENERAL ELECTRIC COMPANY | 2004-09-14 | — | — | US | disclosed |
| EP-1233997-B1 | METHOD FOR PURIFICATION OF AROMATIC POLYETHERS | GEN ELECTRIC (US) | 2003-09-03 | — | — | EP | disclosed |
| US-20020151675-A1 | Method for purification of aromatic polyethers | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2002-10-17 | — | — | US | disclosed |
| US-6265521-B1 | USING ALKALI METAL SALT OF A DIHYDROXY-SUBSTITUTED AROMATIC HYDROCARBON | GENERAL ELECTRIC COMPANY | 2001-07-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060173158-A1 | Phase transfer catalyzed method for preparation of polyetherimides | TRRAP, RCC1, DDT | MEN1 4568/4885KMT2A 326/4885HSPA1A 2941/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.