SCHEMBL1735130

SCHEMBL1735130

COc1ccc(OC)c(-n2c3ccccc3c3ccccc32)c1

nearest known ligand 0.68

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.68
ALDH1A1 P00352 7/20 0.54
HPGD P15428 3/20 0.54
L3MBTL1 Q9Y468 3/20 0.54
HTT P42858 2/20 0.54
KDM4E B2RXH2 2/20 0.54
MEN1 O00255 1/20 0.54
KMT2A Q03164 1/20 0.54
HSD17B10 Q99714 1/20 0.54
LMNA P02545 3/20 0.54
GAA P10253 1/20 0.48
CA12 O43570 1/20 0.46
CA1 P00915 1/20 0.46
CA2 P00918 1/20 0.46
CA7 P43166 1/20 0.46
CA9 Q16790 1/20 0.46
CA14 Q9ULX7 1/20 0.46
TSHR P16473 1/20 0.45
MMP10 P09238 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15455938 0.83 MAPT (0.68) MAPTALDH1A1HPGDL3MBTL1HTT
SCHEMBL15453666 0.82 MAPT (0.47) MAPTALDH1A1L3MBTL1HTTKDM4E
SCHEMBL28181208 0.80 MGLL (0.47) MAPTALDH1A1HPGDL3MBTL1HTT
SCHEMBL4267915 0.80 MAPT (0.51) MAPTALDH1A1HPGDL3MBTL1HTT
SCHEMBL18639317 0.77 MAPT (0.48) MAPTALDH1A1HPGDL3MBTL1HTT
SCHEMBL18639316 0.76 ALDH1A1 (0.53) MAPTALDH1A1HPGDL3MBTL1HTT
SCHEMBL14407598 0.75 MAPT (0.70) MAPTALDH1A1HPGDL3MBTL1HTT
SCHEMBL14454763 0.74 KDM4E (0.55) MAPTALDH1A1HPGDL3MBTL1HTT
SCHEMBL30352484 0.73 MAPT (0.68) MAPTALDH1A1HPGDL3MBTL1HTT
SCHEMBL533613 0.73 KDM4E (0.68) MAPTALDH1A1HPGDL3MBTL1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103524518-B Rotaviral tetraene fluorescent compound, preparation method and application thereof, and electroluminescent device TCL集团股份有限公司 2017-05-10 CN claimed
CN-103524518-A Rotaviral tetraene fluorescent compound, preparation method and application thereof, and electroluminescent device TCL GROUP CO LTD 2014-01-22 CN claimed
EP-2162457-B1 CARBAZOLYL POLYMERS FOR ORGANIC ELECTRONIC DEVICES BOE TECHNOLOGY GROUP CO LTD (CN) 2018-08-22 EP disclosed
CN-103524518-B Rotaviral tetraene fluorescent compound, preparation method and application thereof, and electroluminescent device TCL集团股份有限公司 2017-05-10 CN disclosed
CN-101558039-B Carbazolyl monomers and polymers GEN ELECTRIC 2015-04-08 CN disclosed
CN-101801986-B Carbazolyl polymers for organic electronic devices GEN ELECTRIC 2014-12-24 CN disclosed
CN-103524518-A Rotaviral tetraene fluorescent compound, preparation method and application thereof, and electroluminescent device TCL GROUP CO LTD 2014-01-22 CN disclosed
CN-102702074-A Sulfonyl chloride compound taking carbazole as fluorogen and preparation method and application thereof UNIV YANGZHOU 2012-10-03 CN disclosed
EP-2102160-B1 CARBAZOLYL MONOMERS AND POLYMERS GEN ELECTRIC (US) 2011-11-16 EP disclosed
US-20110262920-A1 METHODS FOR PREDICTING SURVIVAL IN CANCER PATIENTS CITY OF HOPE 2011-10-27 US disclosed
US-7851579-B2 Monomers comprising carbazole units and polymers, dendrimers, and hyper-branched materials derived therefrom; OLEDs having device quantum efficiencies, while still maintaining the potential for the molecules to host red, green, and blue emissive complexes GENERAL ELECTRIC COMPANY (US) 2010-12-14 US disclosed
WO-2009023335-A2 CARBAZOLYL POLYMERS FOR ORGANIC ELECTRONIC DEVICES GENERAL ELECTRIC COMPANY (US) 2009-02-19 WO disclosed
WO-2009023335-A2 CARBAZOLYL POLYMERS FOR ORGANIC ELECTRONIC DEVICES GENERAL ELECTRIC COMPANY (US) 2009-02-19 WO disclosed
WO-2008073694-A1 CARBAZOLYL MONOMERS AND POLYMERS GENERAL ELECTRIC COMPANY (US) 2008-06-19 WO disclosed
US-20080138625-A1 CARBAZOLYL MONOMERS AND POLYMERS GENERAL ELECTRIC COMPANY (US) 2008-06-12 US disclosed
US-20080138625-A1 CARBAZOLYL MONOMERS AND POLYMERS GENERAL ELECTRIC COMPANY (US) 2008-06-12 US disclosed
US-20080138625-A1 CARBAZOLYL MONOMERS AND POLYMERS GENERAL ELECTRIC COMPANY (US) 2008-06-12 US disclosed
US-20080135806-A1 CARBAZOLYL POLYMERS FOR ORGANIC ELECTRONIC DEVICES GENERAL ELECTRIC COMPANY (US) 2008-06-12 US disclosed
US-20080135806-A1 CARBAZOLYL POLYMERS FOR ORGANIC ELECTRONIC DEVICES GENERAL ELECTRIC COMPANY (US) 2008-06-12 US disclosed
US-20080135806-A1 CARBAZOLYL POLYMERS FOR ORGANIC ELECTRONIC DEVICES GENERAL ELECTRIC COMPANY (US) 2008-06-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080138625-A1 CARBAZOLYL MONOMERS AND POLYMERS CBR3, C1S, C3AR1 MAPT 4110/4885ALDH1A1 2161/4885HPGD 937/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.