SCHEMBL17351815

SCHEMBL17351815

Fc1cc(F)c(F)c(CS)c1

nearest known ligand 0.41

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
RIPK1 Q13546 8/20 0.41
CES2 O00748 1/20 0.38
CES1 P23141 1/20 0.38
IDO1 P14902 2/20 0.33
DCLRE1B Q9H816 1/20 0.33
GPR84 Q9NQS5 1/20 0.32
DPP4 P27487 1/20 0.31
FAP Q12884 1/20 0.31
DPP8 Q6V1X1 1/20 0.31
DPP9 Q86TI2 1/20 0.31
DPP7 Q9UHL4 1/20 0.31
AGXT P21549 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17058080 0.76 ALDH1A1 (0.34) IDO1DCLRE1BGPR84AGXT
SCHEMBL7984357 0.76 ERN1 (0.42) RIPK1CES2CES1IDO1DCLRE1B
SCHEMBL489929 0.75 RIPK1 (0.41) RIPK1CES2CES1IDO1GPR84
SCHEMBL10195688 0.75 RIPK1 (0.49) RIPK1CES2CES1GPR84
SCHEMBL29518822 0.75 RIPK1 (0.44) RIPK1CES2CES1GPR84DPP4
SCHEMBL6283166 0.75 RIPK1 (0.41) RIPK1CES2CES1IDO1GPR84
SCHEMBL17552647 0.75 RIPK1 (0.41) RIPK1CES2CES1IDO1GPR84
SCHEMBL147511 0.75 RIPK1 (0.41) RIPK1CES2CES1IDO1GPR84
SCHEMBL20560658 0.75 RIPK1 (0.41) RIPK1CES2CES1IDO1GPR84
SCHEMBL698821 0.75 RIPK1 (0.44) RIPK1CES2CES1GPR84DPP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9963451-B2 Fused ring pyrimidine compound and pest control agent containing the same MITSUI CHEMICALS AGRO, INC. (JP) 2018-05-08 US disclosed
US-20150368249-A1 FUSED RING PYRIMIDINE COMPOUND AND PEST CONTROL AGENT CONTAINING THE SAME MITSUI CHEMICALS CROP & LIFE SOLUTIONS, INC. (JP) 2015-12-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150368249-A1 FUSED RING PYRIMIDINE COMPOUND AND PEST CONTROL AGENT CONTAINING THE SAME CBR3, HRH2, HRH4 RIPK1 2092/4885CES2 4030/4885CES1 3844/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.