SCHEMBL6283166

SCHEMBL6283166

Fc1cc(F)c(F)c(CP)c1

nearest known ligand 0.41

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
RIPK1 Q13546 8/20 0.41
CES2 O00748 1/20 0.38
CES1 P23141 1/20 0.38
GPR84 Q9NQS5 1/20 0.32
IDO1 P14902 1/20 0.30
AGXT P21549 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17351815 0.75 RIPK1 (0.41) RIPK1CES2CES1GPR84IDO1
SCHEMBL698821 0.75 RIPK1 (0.44) RIPK1CES2CES1GPR84
SCHEMBL29518822 0.75 RIPK1 (0.44) RIPK1CES2CES1GPR84
SCHEMBL489929 0.75 RIPK1 (0.41) RIPK1CES2CES1GPR84IDO1
SCHEMBL10195688 0.75 RIPK1 (0.49) RIPK1CES2CES1GPR84
SCHEMBL2652556 0.75 RIPK1 (0.44) RIPK1CES2CES1GPR84IDO1
SCHEMBL17552647 0.75 RIPK1 (0.41) RIPK1CES2CES1GPR84IDO1
SCHEMBL147511 0.75 RIPK1 (0.41) RIPK1CES2CES1GPR84IDO1
SCHEMBL20560658 0.75 RIPK1 (0.41) RIPK1CES2CES1GPR84IDO1
SCHEMBL855027 0.75 RIPK1 (0.41) RIPK1CES2CES1GPR84IDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6919291-B2 Fluorinated zwitterionic cocatalyst activators for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. (US) 2005-07-19 US disclosed
US-20040110631-A1 Fluorinated zwitterionic cocatalyst activators for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. 2004-06-10 US disclosed
CN-1477995-A Fluorinated zwitterionic cocatalyst activators for olefin polymerization 埃克森美孚化学专利公司 2004-02-25 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040110631-A1 Fluorinated zwitterionic cocatalyst activators for olefin polymerization FZD7, FOS, COG4 RIPK1 1519/4885CES2 1566/4885CES1 3081/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.