SCHEMBL17352120

SCHEMBL17352120

COP(=O)(CC(=O)Oc1ccc(F)c(C(F)(F)F)c1)OC

nearest known ligand 0.41

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 1/20 0.39
SLC6A4 P31645 1/20 0.39
KCNH2 Q12809 1/20 0.39
EPHX2 P34913 5/20 0.39
PTPN7 P35236 1/20 0.36
DUSP3 P51452 1/20 0.36
CDK8 P49336 1/20 0.36
TAS1R3 Q7RTX0 2/20 0.36
TAS1R1 Q7RTX1 2/20 0.36
TAS1R2 Q8TE23 2/20 0.36
KCNN4 O15554 1/20 0.35
AR P10275 1/20 0.34
PLA2G7 Q13093 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17356501 0.87 HTR2A (0.40) HTR2ASLC6A4KCNH2EPHX2PTPN7
SCHEMBL17352172 0.87 HTR2A (0.36) HTR2ASLC6A4KCNH2EPHX2PTPN7
SCHEMBL17356491 0.86 TRPM8 (0.38) HTR2ASLC6A4KCNH2EPHX2CDK8
SCHEMBL17356512 0.86 SMN1; SMN2 (0.37) HTR2ASLC6A4KCNH2EPHX2CDK8
SCHEMBL17356506 0.85 PTPN7 (0.40) HTR2ASLC6A4KCNH2EPHX2PTPN7
SCHEMBL17356492 0.84 GAA (0.39) PTPN7DUSP3
SCHEMBL17355831 0.82 TDP1 (0.40) HTR2ASLC6A4KCNH2
SCHEMBL17356437 0.80 ACHE (0.47) HTR2ASLC6A4KCNH2PTPN7DUSP3
SCHEMBL17356472 0.80 CDK8 (0.44) HTR2ASLC6A4KCNH2EPHX2PTPN7
SCHEMBL17352167 0.80 MAPT (0.44) HTR2ASLC6A4KCNH2EPHX2PTPN7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150372349-A1 NON-AQUEOUS ELECTROLYTE AND ELECTRICITY STORAGE DEVICE UBE INDUSTRIES, LTD. (JP) 2015-12-24 US disclosed
US-20150372349-A1 NON-AQUEOUS ELECTROLYTE AND ELECTRICITY STORAGE DEVICE UBE INDUSTRIES, LTD. (JP) 2015-12-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150372349-A1 NON-AQUEOUS ELECTROLYTE AND ELECTRICITY STORAGE DEVICE HCN2, SCO2, HCN1 HTR2A 4567/4885SLC6A4 2741/4885KCNH2 4/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.