Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM5 | P08912 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
| ▸ | AVPR1B | P47901 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | ITK | Q08881 | 1/20 | 0.42 |
| ▸ | CCR3 | P51677 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.41 |
| ▸ | CSF1R | P07333 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | FLT3 | P36888 | 1/20 | 0.40 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.40 |
| ▸ | MERTK | Q12866 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1736528 | 1.00 | CHRM5 (0.43) | CHRM5CHRM1CHRM3DRD3LTA4H | |
| SCHEMBL1735437 | 0.91 | KDM4E (0.49) | EGFRITKHRH3KMT2AKDM4E | |
| SCHEMBL1735361 | 0.90 | OPRM1 (0.44) | CHRM5CHRM1CHRM3LTA4HHRH3 | |
| SCHEMBL1735308 | 0.88 | DRD3 (0.51) | DRD3MEN1KMT2AKDM4E | |
| SCHEMBL1735305 | 0.88 | DRD3 (0.51) | DRD3MEN1KMT2AKDM4E | |
| SCHEMBL1734298 | 0.87 | DRD3 (0.48) | DRD3LTA4HCCR3HRH3CSF1R | |
| SCHEMBL1735428 | 0.86 | HRH3 (0.45) | CHRM5CHRM1CHRM3HRH3DGAT1 | |
| SCHEMBL1735370 | 0.86 | JAK2 (0.44) | EGFRITKHRH3KDM4EFLT3 | |
| SCHEMBL13605487 | 0.84 | DRD3 (0.44) | DRD3LTA4HMEN1KMT2A | |
| SCHEMBL13605442 | 0.83 | LMNA (0.59) | DRD3KDM4ELMNAGLASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1928236-B1 | DIARYLAMINE-CONTAINING COMPOUNDS AND COMPOSITIONS, AND THEIR USE AS MODULATORS OF C-KIT RECEPTORS | IRM LLC (BM) | 2011-11-23 | — | — | EP | claimed |