Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 2/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | GSK3B | P49841 | 1/20 | 0.42 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.42 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | HTR1D | P28221 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | HTR7 | P34969 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | CDK1 | P06493 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1736462 | 0.90 | KCNA5 (0.47) | HDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL1735352 | 0.90 | CHRM5 (0.43) | CHRM5CHRM1CHRM3HRH3LTA4H | |
| SCHEMBL1736528 | 0.90 | CHRM5 (0.43) | CHRM5CHRM1CHRM3HRH3LTA4H | |
| SCHEMBL1735359 | 0.89 | OPRM1 (0.46) | OPRM1SIGMAR1CACNA1GHTR1AHTR1D | |
| Hydrochloric Acid SCHEMBL1734487 | 0.88 | OPRM1 (0.45) | OPRM1SIGMAR1CACNA1GHTR1AHTR1D | |
| SCHEMBL1734200 | 0.87 | OPRM1 (0.44) | OPRM1SIGMAR1GSK3BHTR1AHRH3 | |
| SCHEMBL1735370 | 0.87 | JAK2 (0.44) | SIGMAR1HRH3HDAC3HDAC1HDAC2 | |
| SCHEMBL1734153 | 0.87 | CACNA1G (0.45) | OPRM1SIGMAR1CACNA1GHTR1AHTR1D | |
| SCHEMBL13605739 | 0.87 | CACNA1G (0.45) | OPRM1SIGMAR1GSK3BCACNA1GHTR1A | |
| SCHEMBL1735198 | 0.86 | AVPR1B (0.48) | OPRM1SIGMAR1CACNA1GHTR1AHTR1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1928236-B1 | DIARYLAMINE-CONTAINING COMPOUNDS AND COMPOSITIONS, AND THEIR USE AS MODULATORS OF C-KIT RECEPTORS | IRM LLC (BM) | 2011-11-23 | — | — | EP | claimed |